Lemborexant 5 mg

DRUG7 trials

Conditions

Cardiac SurgeryCardiac Surgery SubjectsDelirium - PostoperativeDementiaFeasibility StudiesFrontotemporal DementiaHealthy ParticipantsIn-hospital Mortality

Phase 1

Study to Evaluate the Effect of 2 Dosage Strengths of Lemborexant (E2006) on a Multiple Sleep Latency Test in Participants With Insomnia Disorder

CompletedNCT02350309

Eisai Inc.Insomnia Disorder

Start: 2014-12-13End: 2015-04-21Updated: 2020-01-18

Study to Evaluate the Effect of Lemborexant Versus Placebo on Driving Performance in Healthy Adult and Elderly Subjects

CompletedNCT02583451

Eisai Inc.Healthy Participants

Start: 2015-11-30End: 2017-02-28Updated: 2018-09-06

Phase 2

Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia

CompletedNCT03001557

Eisai Inc.Irregular Sleep-Wake Rhythm Disorder

Start: 2016-12-20End: 2020-04-17Updated: 2021-05-17

Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients

Not yet recruitingNCT06648681

University of British ColumbiaCardiac Surgery, Cardiac Surgery Subjects, Delirium - Postoperative +4

Start: 2025-05-01End: 2027-04-30Target: 60Updated: 2025-04-23

Lemborexant on Perioperative Sleep Quality in Patients Undergoing Thoracoscopic Surgery

Not yet recruitingNCT07811401

Beijing Tiantan HospitalPostoperative Sleep Disturbance, Thoracoscopic Surgery

Start: 2026-10-08End: 2028-06-01Target: 130Updated: 2026-09-10

Phase 4

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

RecruitingNCT06093126

Nova Scotia Health AuthorityDementia, Frontotemporal Dementia, Insomnia

Start: 2023-12-11End: 2028-12-11Target: 1Updated: 2025-02-21

Unknown Phase

Patient-Reported Outcomes for Lemborexant in Chinese Participants With Insomnia

RecruitingNCT06225947

Guangdong Provincial People's HospitalInsomnia

Start: 2024-02-22End: 2025-06-30Target: 200Updated: 2024-07-30

SLEEP2025-05-01

Efficacy and safety of insomnia treatment with lemborexant in older adults: analyses from three clinical trials

Drugs & Aging2024-08-0910 citations

Assessment of morning sleep propensity with lemborexant in adults with insomnia disorder in a randomized, placebo-controlled crossover study

SLEEP Advances2021-03-015 citations

Long‐term safety and efficacy of lemborexant in subjects with irregular sleep‐wake rhythm disorder and Alzheimer’s disease dementia

Alzheimer s & Dementia2020-12-01

F1‐06‐04: RESPONSE TO TREATMENT WITH LEMBOREXANT: SUBJECTS WITH IRREGULAR SLEEP‐WAKE RHYTHM DISORDER AND ALZHEIMER'S DISEASE DEMENTIA

Alzheimer s & Dementia2019-07-014 citations

On-the-road driving performance the morning after bedtime administration of lemborexant in healthy adult and elderly volunteers

SLEEP2018-12-31225 citations