Ledipasvir

DRUG6 trials

Conditions

Chronic Hepatitis C InfectionCirrhosisHIV InfectionHepatitis CHepatitis C, ChronicHepatocellular Carcinoma

Phase 2

Combination Therapy for Chronic Hepatitis C Infection

National Institute of Allergy and Infectious Diseases (NIAID)Hepatitis C, Chronic

Start: 2013-01-31End: 2015-08-31Updated: 2017-06-08

Feasibility, Tolerance and Efficacy of Interferon-free, Antiviral Treatment With Sofosbuvir + Ribavirin for the Treatment of Genotype 2 and Sofosbuvir/Ledipasvir for the Treatment of Genotype 1 and 4 Hepatitis C Virus-infected Patients in West and Central Africa

CompletedNCT02405013

ANRS, Emerging Infectious DiseasesHepatitis C, HIV Infection

Start: 2015-10-31End: 2017-11-30Updated: 2017-12-13

Phase 3

Sofosbuvir, Ledipasvir, Ribavirin for Hepatitis C Cirrhotics, Genotype 1

CompletedNCT02705534

Tehran University of Medical SciencesCirrhosis, Hepatitis C

Start: 2016-09-30End: 2017-10-31Updated: 2018-04-30

Impact of Interferon Free Regimens in Patients With Chronic HCV and Successfully Treated HCC

NCT02771405

National Hepatology & Tropical Medicine Research InstituteHepatitis C, Chronic, Hepatocellular Carcinoma

Start: 2016-03-31End: 2019-09-30Target: 150Updated: 2016-05-13

Phase 4

Program of Screening, Prevention and Elimination of Hepatitis C in Penitentiary Institutions in Cantabria (JAILFREE-C)

CompletedNCT02768961

Instituto de Investigación Marqués de ValdecillaHepatitis C

Start: 2016-05-10End: 2017-05-10Updated: 2017-05-18

Unknown Phase

Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions

CompletedNCT02333292

Valme University HospitalChronic Hepatitis C Infection

Start: 2014-12-31End: 2017-06-30Updated: 2022-06-29

Journal of Antimicrobial Chemotherapy2023-09-064 citations

Patient-reported outcomes with direct-acting antiviral treatment for hepatitis C in West and Central Africa (TAC ANRS 12311 trial).

2022-12-284 citations

Impact of recent drug use on the efficacy of elbasvir/grazoprevir for HCV‐infected people on opioid agonist therapy

Journal of Viral Hepatitis2021-03-15

Response to direct-acting antiviral therapy among ongoing drug users and people receiving opioid substitution therapy.

2019-03-0843 citations

Hepatitis C virus treatment by direct-acting antivirals in successfully treated hepatocellular carcinoma and possible mutual impact

European Journal of Gastroenterology & Hepatology2018-05-0420 citations

Effect of HIV co-infection on adherence to a 12-week regimen of hepatitis C virus therapy with ledipasvir and sofosbuvir.

2016-01-0121 citations

Four-Week Direct-Acting Antiviral Regimens in Noncirrhotic Patients With Hepatitis C Virus Genotype 1 Infection: An Open-Label, Nonrandomized Trial.

2015-11-2451 citations

Successful Retreatment of Chronic HCV Genotype-1 Infection With Ledipasvir and Sofosbuvir After Initial Short Course Therapy With Direct-Acting Antiviral Regimens

Clinical Infectious Diseases2015-10-3151 citations

Ledipasvir and sofosbuvir for hepatitis C genotype 4: a proof-of-concept, single-centre, open-label phase 2a cohort study.

2015-07-14109 citations

Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study.

2015-01-13120 citations

Re-treatment of chronic hepatitis C virus genotype 1 infection after relapse: an open-label pilot study.

2014-11-0151 citations