Lansoprazole Placebo

DRUG7 trials

Sponsors

Takeda, Jiangsu Sinorda Biomedicine Co., Ltd, Il-Yang Pharm. Co., Ltd.

Conditions

Duodenal UlcerErosive EsophagitisGastric UlcerPeptic UlcerReflux Esophagitis

Phase 2

Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis

CompletedNCT04531475

Jiangsu Sinorda Biomedicine Co., LtdReflux Esophagitis

Start: 2020-01-21End: 2021-01-12Updated: 2025-07-17

Phase 3

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in the Maintenance Treatment of Erosive Esophagitis

CompletedNCT02388737

TakedaErosive Esophagitis

Start: 2015-04-01End: 2018-12-31Updated: 2020-02-21

Efficacy and Safety of Oral Once-Daily Vonoprazan (TAK-438) in Participants With Erosive Esophagitis

CompletedNCT02388724

TakedaErosive Esophagitis

Start: 2015-03-24End: 2017-07-27Updated: 2019-06-03

Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection

CompletedNCT03050307

TakedaGastric Ulcer

Start: 2017-04-17End: 2020-05-26Updated: 2021-06-18

Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection

CompletedNCT03050359

TakedaDuodenal Ulcer

Start: 2017-04-05End: 2019-07-19Updated: 2020-06-12

Study to Evaluate the Efficacy and Safety of Ilaprazole 10 mg in Prevention NSAIDs Associated Peptic Ulcer

RecruitingNCT06284876

Il-Yang Pharm. Co., Ltd.Peptic Ulcer

Start: 2024-07-23End: 2027-02-28Target: 416Updated: 2025-05-30

The Phase III Clinical Trial of X842 Capsules for Reflux Esophagitis

CompletedNCT07079540

Jiangsu Sinorda Biomedicine Co., LtdReflux Esophagitis

Start: 2021-06-24End: 2022-12-01Updated: 2025-07-23

Related Papers

Vonoprazan 10 mg or 20 mg vs. lansoprazole 15 mg as maintenance therapy in Asian patients with healed erosive esophagitis: A randomized controlled trial

Chinese Medical Journal2024-03-2910 citations

Efficacy and Safety of Vonoprazan-Based Quadruple Therapy for the Eradication of Helicobacter pylori in Patients with Peptic Ulcers: A Pooled Analysis of Two Randomized, Double-Blind, Double-Dummy, Phase 3 Trials.

2024-01-014 citations

Phase III, randomised, double-blind, multicentre study to evaluate the efficacy and safety of vonoprazan compared with lansoprazole in Asian patients with erosive oesophagitis

Gut2019-08-13139 citations