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Landiolol

DRUG10 trials

Sponsors

Yamamoto Ryo, Hirosaki university hospital, Hospices Civils de Lyon, University Hospital, Caen, CMC Ambroise Paré

Conditions

Atrial FibrillationAutonomic DysfunctionBeta BlockerBeta-blockerCardiac ArrestCardiac FailureCardiac SurgeryCardiovascular (CV) Risk

Phase 1

Beta-blockade With Landiolol in Out-of-hospital Cardiac Arrest
NCT05554978
Medical University of ViennaCardiac Arrest
Start: 2021-03-03End: 2023-12-31Target: 32Updated: 2023-03-17

Phase 3

Landiolol in Postoperative Atrial Fibrillation
CompletedNCT03779178
Hospices Civils de LyonAtrial Fibrillation
Start: 2019-01-17End: 2019-12-04Updated: 2025-08-06
Prevention of Atrial Fibrillation by Low-dose Landiolol Administration After Cardiac Surgery
CompletedNCT04607122
CMC Ambroise ParéAtrial Fibrillation, Cardiac Surgery
Start: 2021-01-27End: 2023-07-22Updated: 2026-04-08
Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility
RecruitingNCT04748796
Centre Hospitalier Universitaire, AmiensBeta-blocker, Mortality During Septic Shock, Septic Shock +1
Start: 2021-02-01End: 2027-09-30Target: 360Updated: 2025-08-24
LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS)
RecruitingNCT04931225
Assistance Publique - Hôpitaux de ParisSeptic Shock
Start: 2022-07-18End: 2026-07-31Target: 44Updated: 2025-08-01
Evaluating Multiple Treatments and Strategies for Sepsis in Adaptive Platform trial
RecruitingJPRN-jRCT1031240424
Yamamoto RyoSepsis septic shock
Start: 2024-11-14Target: 1640Updated: 2026-06-29

Phase 4

Comparison of Two Strategies for the Management of Atrial Fibrillation After Cardiac Surgery
NCT04223739
University Hospital, CaenAtrial Fibrillation, Cardiac Surgery
Start: 2019-12-13End: 2022-06-01Target: 380Updated: 2020-01-10
Landiolol in Mitral Valve Surgery
RecruitingNCT06793670
Università Vita-Salute San RaffaeleCardiac Failure, Low Cardiac Output Syndrome
Start: 2025-01-28End: 2027-12-31Target: 1500Updated: 2025-12-29
LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery
RecruitingNCT07168421
Insel Gruppe AG, University Hospital BernAutonomic Dysfunction, Beta Blocker, Cardiovascular (CV) Risk +3
Start: 2026-04-24End: 2028-03-01Target: 114Updated: 2026-05-05

Unknown Phase

A study on efficacy of autonomic nerve regulating agents on manifestation of accessory pathway in paroxysmal supraventricular tachycardia patients
Active, not recruitingJPRN-UMIN000030753
Hirosaki university hospitalParoxysmal supraventricular tachycardia (PSVT)
Start: 2018-01-15Target: 50Updated: 2026-06-29

Related Papers

Low dose of landiolol does not prevent postoperative atrial fibrillation after cardiac surgery in non-Asian patients: a multicentre randomised study.
2025-11-06
Comparison of landiolol and amiodarone for the treatment of new-onset atrial fibrillation after cardiac surgery (FAAC) trial: study protocol for a randomized controlled trial.
2023-05-253 citations