JAK Inhibitor
Sponsors
Fred Hutchinson Cancer Center, Liga Panamericana de Asociaciones de Reumatologia (PANLAR), First Affiliated Hospital Xi'an Jiaotong University, Abu Dhabi Stem Cells Center, Humanitas Clinical and Research Center
Conditions
Aicardi-Goutières Syndrome (AGS)Antisynthetase SyndromeArthritis, PsoriaticArthritis, RheumatoidDermatomyositis, Adult TypeImmune Checkpoint Inhibitors (ICI)-Related DermatitisInterstitial Lung Disease (ILD)Myelodysplastic/Myeloproliferative Neoplasm
Phase 2
Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis
RecruitingNCT04370301
Start: 2021-02-09End: 2029-08-31Target: 20Updated: 2026-01-12
JAK Inhibitors for Solid Malignant Tumor Patients With Immune Checkpoint Inhibitors-related Dermatitis: A Open-lable, Single Arm, Phase IIa Trial
RecruitingNCT06715982
Start: 2024-12-31End: 2025-12-31Target: 35Updated: 2025-10-28
Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes
RecruitingNCT07228624
Start: 2026-02-04End: 2030-09-01Target: 50Updated: 2026-02-19
Phase 3
Phase 4
Unknown Phase
PANLAR's Latin American Registry of Rheumatic Patients Treated With Jak Inhibitors
NCT04821206
Start: 2021-03-01End: 2024-07-01Target: 3000Updated: 2021-03-29
The PODIUM Study - a Three-arm Comparison of Target Therapies After Anti-TNFα in Ulcerative Colitis
RecruitingNCT06691061
Start: 2023-08-01End: 2024-12-31Target: 450Updated: 2024-11-15
Evaluate the Efficacy of Anti-Jak1 Inhibitors as Treatment for Patients With Aicardi-Goutières Syndrome
CompletedNCT06898372
Start: 2024-04-07End: 2024-12-18Updated: 2025-03-27
A Study on the Efficacy and Safety of JAK Inhibitors Versus Calcineurin Inhibitors as Initial Therapy for Interstitial Lung Disease Associated With Antisynthetase Syndrome
Not yet recruitingNCT07406932
Start: 2026-02-01End: 2027-07-01Target: 80Updated: 2026-02-12