IXIARO

BIOLOGICAL6 trials

Conditions

Humoral and Cellular Immune ResponsesInfectious DiseaseJapanese EncephalitisJapanese Encephalitis Virus DiseaseViral InfectionYellow FeverZika Virus Infection

Phase 1

Immune Response in IXIARO Batch JEV09L37 Recipients Before and After Revaccination

WithdrawnNCT01559831

Valneva Austria GmbHJapanese Encephalitis

Start: 2012-06-30End: 2013-03-31Updated: 2013-03-08

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

CompletedNCT02963909

National Institute of Allergy and Infectious Diseases (NIAID)Zika Virus Infection

Start: 2016-11-01End: 2018-10-30Updated: 2024-04-22

A Study to Assess the Safety, Reactogenicity, and Immunogenicity of SK Japanese Encephalitis Messenger Ribonucleic Acid (mRNA) Vaccines (GBP560) in Healthy Adults

RecruitingNCT06680128

SK Bioscience Co., Ltd.Japanese Encephalitis Virus Disease

Start: 2025-02-24End: 2028-03-19Target: 402Updated: 2025-12-23

Phase 2

An Experimental Medicine Decipher of a Minimum Correlate of Cellular Immunity

NCT05568953

Singapore General HospitalInfectious Disease, Japanese Encephalitis, Viral Infection +1

Start: 2022-09-28End: 2025-10-31Target: 70Updated: 2023-04-12

Phase 3

Open-label, Randomized Study in a Pediatric Population in a JEV (Japanese Encephalitis Virus)-Endemic Country

CompletedNCT01296360

Valneva Austria GmbHJapanese Encephalitis

Start: 2010-12-31End: 2013-10-31Updated: 2014-12-19

Phase 4

Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis Vaccine

CompletedNCT01398540

Medical University of ViennaHumoral and Cellular Immune Responses

Start: 2010-11-30End: 2013-11-30Updated: 2018-03-29

Related Papers

Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans.

2025-01-1022 citations

Safety and immunogenicity of a purified inactivated Zika virus vaccine candidate in adults primed with a Japanese encephalitis virus or yellow fever virus vaccine in the USA: a phase 1, randomised, double-blind, placebo-controlled clinical trial.

2023-06-2715 citations

An experimental medicine decipher of a minimum correlate of cellular immunity: Study protocol for a double-blind randomized controlled trial

Frontiers in Immunology2023-03-104 citations

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.

2017-12-05230 citations

Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials.

2017-12-05156 citations