IV Methylnaltrexone (MNTX)

DRUG5 trials

Sponsors

Bausch Health Americas, Inc.

Conditions

Healthy AdultsHealthy Male VolunteersHealthy MalesHealthy SubjectsPostoperative Ileus

Phase 1

Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan

CompletedNCT01367535

Bausch Health Americas, Inc.Healthy Adults

Start: 2006-03-31End: 2006-08-31Updated: 2019-11-27

Pharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous Dose

CompletedNCT01367496

Bausch Health Americas, Inc.Healthy Subjects

Start: 2002-06-30End: 2002-08-31Updated: 2019-11-27

Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function

CompletedNCT01367561

Bausch Health Americas, Inc.Healthy Males

Start: 2002-10-31End: 2003-05-31Updated: 2023-04-12

Study of the Pharmacokinetics of Intravenous Administered 14C-MNTX

CompletedNCT01367483

Bausch Health Americas, Inc.Healthy Male Volunteers

Start: 2005-06-30End: 2005-06-30Target: 6Updated: 2019-11-27

Phase 2

Intravenous (IV) Methylnaltrexone (MNTX) in the Prevention of Post-Operative Ileus

CompletedNCT01367548

Bausch Health Americas, Inc.Postoperative Ileus

Start: 2003-07-31End: 2004-12-31Updated: 2019-11-27