Isotonic crystalloids

DRUG3 trials

Sponsors

Anders Perner, Anders Perner, MD, PhD, Marie Kristine Jessen, MD

Conditions

SepsisSeptic Shock

Phase 2

Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients

CompletedNCT05076435

Marie Kristine Jessen, MDSepsis

Start: 2021-11-03End: 2022-03-19Updated: 2022-03-25

Phase 4

Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care

CompletedNCT02079402

Anders PernerSepsis, Septic Shock

Start: 2014-09-30End: 2015-11-30Updated: 2015-12-09

The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial

CompletedNCT03668236

Anders Perner, MD, PhDSeptic Shock

Start: 2018-11-27End: 2022-11-16Updated: 2025-02-24

Related Papers

Effects of <scp>IV</scp> fluid restriction according to site‐specific intensity of standard fluid treatment—protocol

Acta Anaesthesiologica Scandinavica2024-04-041 citations

Restriction of Intravenous Fluid in ICU Patients with Septic Shock

New England Journal of Medicine2022-06-17345 citations

Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients (REFACED Sepsis)-protocol for a multicenter, randomized, clinical, proof-of-concept trial.

2022-03-291 citations

Lower vs Higher Fluid Volumes During Initial Management of Sepsis: A Systematic Review With Meta-Analysis and Trial Sequential Analysis.

2020-01-2369 citations

Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial.

2016-09-30255 citations