Isosorbide Dinitrate

DRUG17 trials

Sponsors

National Heart, Lung, and Blood Institute (NHLBI), Satish R. Raj, Parent Project, Italy, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Corporal Michael J. Crescenz VA Medical Center

Conditions

A Feasibility Study on Hypertensive Heart Failure TreatmentAcute Coronary SyndromeAcute Heart FailureCardio-Renal SyndromeCardiovascular DiseasesCervical PregnancyChronic Orthostatic IntoleranceCongestive Heart Failure

Phase 1

Treatment of Orthostatic Intolerance

Active, not recruitingNCT00262470

Satish R. RajChronic Orthostatic Intolerance, Tachycardia

Start: 1997-04-30End: 2029-12-31Target: 150Updated: 2025-10-08

To Compare the Pharmacokinetics Profiles of ISO 20, IBU 200 and IBU Plus ISO Combinations 200 + 20

CompletedNCT01478022

Parent Project, ItalyDuchenne Muscular Dystrophy (DMD)

Start: 2011-10-31End: 2016-03-31Updated: 2018-08-31

Phase 2

Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction

CompletedNCT01516346

Corporal Michael J. Crescenz VA Medical CenterCongestive Heart Failure, Heart Failure

Start: 2012-01-31End: 2017-08-18Updated: 2022-06-21

Nitrate Effect on Exercise Capacitance

CompletedNCT04297241

Children's Hospital Medical Center, CincinnatiFontan

Start: 2019-12-12End: 2021-05-03Updated: 2021-09-22

Phase 3

Asymptomatic Cardiac Ischemia Pilot (ACIP) Study

CompletedNCT00000478

National Heart, Lung, and Blood Institute (NHLBI)Cardiovascular Diseases, Coronary Disease, Heart Diseases +1

Start: 1990-11-30End: 1997-06-30Updated: 2016-03-25

Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure

University of Cape TownAcute Heart Failure, Left Ventricular Dysfunction

Start: 2013-01-31End: 2016-07-31Target: 500Updated: 2015-08-14

Nitrates In Combination With Hydralazine in cardiorEnal Syndrome (NICHE) Study

National University Hospital, SingaporeCardio-Renal Syndrome

Start: 2015-01-31End: 2016-06-30Target: 100Updated: 2015-01-22

Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers

CompletedNCT02789033

University of GuadalajaraDiabetic Foot Ulcers

Start: 2015-06-30End: 2015-08-31Updated: 2021-01-12

Phase 4

A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis

CompletedNCT01513070

Guang'anmen Hospital of China Academy of Chinese Medical SciencesCoronary Artery Stenosis, Coronary Heart Disease

Start: 2012-04-30End: 2014-06-30Target: 120Updated: 2014-08-05

Medical Management of Late Intrauterine Death.

CompletedNCT02488642

National Institute of PerinatologyCervical Pregnancy, Maternal Care for Late Fetal Death

Start: 2008-05-31End: 2014-05-31Updated: 2015-07-24

Optimized Treatment of Pulmonary Edema or Congestion

RecruitingNCT05276219

Johannes GrandAcute Heart Failure, Congestive Heart Failure, Pulmonary Edema

Start: 2023-09-14End: 2026-12-31Target: 1104Updated: 2024-12-19

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

RecruitingNCT06218199

Heart Center Research, LLCHeart Failure, Congestive

Start: 2021-07-08End: 2026-12-31Target: 80Updated: 2024-01-29

Hypertensive Heart Failure Treatment in SSA

CompletedNCT06400784

University of AbujaA Feasibility Study on Hypertensive Heart Failure Treatment

Start: 2022-03-25End: 2024-03-26Updated: 2024-05-06

Unknown Phase

Intensive Arterial Pressure Control in Acute Coronary Syndrome

CompletedNCT02135315

University of MonastirAcute Coronary Syndrome

Start: 2014-03-31End: 2020-12-31Updated: 2022-08-24

Non-inferiority of Pharmacological Prevention Alone Versus Pancreatic Stents to Prevent Post-ERCP Pancreatitis

Tehran University of Medical SciencesPancreatitis

Start: 2015-02-28Target: 400Updated: 2015-11-06

Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF

WithdrawnNCT02649998

Chinese University of Hong KongHeart Decompensation

Start: 2017-01-31End: 2022-06-30Updated: 2023-03-21

Adequate Hydration Therapy Combined With Intravenous Infusion of Isosorbide Dinitrate Prevention for CIN

Chinese PLA General HospitalCardio-Renal Syndrome

Start: 2016-03-31End: 2017-04-30Target: 400Updated: 2016-03-24

Related Papers

Isosorbide DiNitrate Effect on Hemodynamic Profile, Liver Stiffness, and Exercise Tolerance in Fontan Circulation (The NEET Clinical Trial).

2023-04-213 citations

N-Terminal pro BNP and Galectin-3 are Prognostic Biomarkers of Acute Heart Failure in Sub-Saharan Africa: Lessons from the BAHEF Trial

ESC Heart Failure2020-11-289 citations

Splanchnic Venous Compression Enhances the Effects of ß-Blockade in the Treatment of Postural Tachycardia Syndrome.

2020-07-1613 citations

A randomized controlled trial comparing isosorbide dinitrate-oxytocin versus misoprostol-oxytocin at management of foetal intrauterine death

PLoS ONE2019-11-211 citations

Prevention of contrast‐induced nephropathy by adequate hydration combined with isosorbide dinitrate for patients with renal insufficiency and congestive heart failure

Clinical Cardiology2018-07-2821 citations

Isosorbide Dinitrate, With or Without Hydralazine, Does Not Reduce Wave Reflections, Left Ventricular Hypertrophy, or Myocardial Fibrosis in Patients With Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association2017-02-0244 citations

Bi Treatment with Hydralazine/Nitrates vs. Placebo in Africans Admitted with Acute HEart Failure (BA-HEF)

European Journal of Heart Failure2016-05-2012 citations

Postural Tachycardia Syndrome and Inappropriate Sinus Tachycardia: Role of Autonomic Modulation and Sinus Node Automaticity

Journal of the American Heart Association2014-03-2453 citations