isoniazid and rifapentine

DRUG3 trials

Sponsors

Centers for Disease Control and Prevention, National Taiwan University Hospital, Huashan Hospital

Conditions

Latent TuberculosisLatent Tuberculosis InfectionTuberculosis

Phase 3

Study 33: Adherence to Latent Tuberculosis Infection Treatment 3HP SAT Versus 3HP DOT

CompletedNCT01582711

Centers for Disease Control and PreventionLatent Tuberculosis Infection

Start: 2012-09-30End: 2014-10-31Updated: 2025-03-13

Risk of SDRs Under 3HP and 1HP Regimen for LTBI

CompletedNCT04094012

National Taiwan University HospitalLatent Tuberculosis Infection

Start: 2019-09-24End: 2023-12-15Updated: 2023-12-26

A Novel Therapy With a 1-Month Ultrashort Regimen to Halt Progression From Latent Infection to Active Tuberculosis Among Close Contacts (The TB-YOUTH Study)

RecruitingNCT06022146

Huashan HospitalLatent Tuberculosis, Tuberculosis

Start: 2023-09-01End: 2026-09-01Target: 3520Updated: 2026-07-14

Related Papers

A Novel One-month Ultra-Short Preventive Treatment for Halting Active Tuberculosis from Latent Infection Among Close Contacts (TB-YOUTH study): Study Protocol For A Cluster-Randomized Controlled Trial (Preprint)

2025-12-15

Efficacy and safety of a novel short course rifapentine and isoniazid regimen for the preventive treatment of tuberculosis in Chinese silicosis patients: a pilot study (SCRIPT-TB)

Emerging Microbes & Infections2025-05-061 citations

One-month daily and three-month weekly rifapentine plus isoniazid are comparable in completion rate and safety for latent tuberculosis infection in non-HIV Population: a randomized controlled trial.

2024-07-107 citations

Symptoms and Systemic Drug Reactions in Persons Receiving Weekly Rifapentine Plus Isoniazid (3HP) Treatment for Latent Tuberculosis Infection

Clinical Infectious Diseases2023-02-2315 citations

Exposure to Latent Tuberculosis Treatment during Pregnancy. The PREVENT TB and the iAdhere Trials

Annals of the American Thoracic Society2018-02-0258 citations

Self-administered Versus Directly Observed Once-Weekly Isoniazid and Rifapentine Treatment of Latent Tuberculosis Infection: A Randomized Trial.

2017-11-07117 citations