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Intravitreal Aflibercept Injection (IAI)

DRUG7 trials

Sponsors

Regeneron Pharmaceuticals, Ophthalmic Consultants of Long Island

Conditions

Age - Related Macular Degeneration (AMD)Chorioretinal Vascular DiseaseDiabetic Macular EdemaNeovascular Age-Related Macular DegenerationProliferative Diabetic Retinopathy

Phase 1

Study of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular (Wet) Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME)
CompletedNCT01997164
Regeneron PharmaceuticalsDiabetic Macular Edema, Neovascular Age-Related Macular Degeneration
Start: 2014-11-30End: 2015-10-31Updated: 2016-01-12

Phase 2

Treatment With Intravitreal Aflibercept Injection For Proliferative Diabetic Retinopathy, The A.C.T Study
CompletedNCT01813773
Ophthalmic Consultants of Long IslandProliferative Diabetic Retinopathy
Start: 2013-03-31End: 2016-04-30Updated: 2016-06-06
Study of Intravitreal REGN2176-3 in Participants With Neovascular (Wet) Age-Related Macular Degeneration (AMD)
TerminatedNCT02418754
Regeneron PharmaceuticalsNeovascular Age-Related Macular Degeneration
Start: 2015-05-05End: 2017-04-03Updated: 2020-10-26
Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema
CompletedNCT02712008
Regeneron PharmaceuticalsDiabetic Macular Edema
Start: 2016-03-02End: 2017-07-10Updated: 2018-10-03
Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection
CompletedNCT02713204
Regeneron PharmaceuticalsNeovascular Age-Related Macular Degeneration
Start: 2016-03-31End: 2017-10-03Updated: 2019-05-07

Phase 4

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)
CompletedNCT01722045
Regeneron PharmaceuticalsAge - Related Macular Degeneration (AMD)
Start: 2012-11-30End: 2015-09-30Updated: 2017-12-22
Study to Evaluate an Aflibercept (EYLEA®) Prefilled Syringe
CompletedNCT03767738
Regeneron PharmaceuticalsChorioretinal Vascular Disease
Start: 2018-12-19End: 2020-08-19Updated: 2021-09-16