Intensive medical management

OTHER7 trials

Conditions

Cardiovascular DiseaseDiabetes MellitusDiabetes Mellitus, Type 2Intracranial Arterial StenosisIntracranial AtherosclerosisIschemic StrokeObesityStenoses, Carotid

Phase 3

Stenting vs. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis

CompletedNCT00576693

Medical University of South CarolinaIschemic Stroke

Start: 2008-10-31End: 2013-04-30Updated: 2018-05-30

Unknown Phase

Laparoscopic Bariatric Surgery to Treat Type 2 Diabetes in Obese Patients

TerminatedNCT00428571

Hamilton Health Sciences CorporationType 2 Diabetes

Start: 2007-05-31End: 2015-04-30Updated: 2016-04-14

DSS: Diabetes Surgery Study - Intensive Medical Management of Type 2 Diabetes, With and Without Gastric Bypass Surgery

CompletedNCT00641251

Medtronic - MITGCardiovascular Disease, Type 2 Diabetes

Start: 2008-02-29End: 2016-12-31Updated: 2017-11-29

Sleeve Gastrectomy Versus Medical Management for Remission of Diabetes in Mild to Moderately Obese Patients

TerminatedNCT00965302

59th Medical WingDiabetes Mellitus, Type 2, Obesity

Start: 2009-08-31End: 2014-09-30Updated: 2023-04-25

Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes

CompletedNCT01429506

Post Graduate Institute of Medical Education and Research, ChandigarhDiabetes Mellitus, Obesity

Start: 2011-01-31End: 2012-08-31Updated: 2015-10-26

CREST-2 Long-term Observational Extension Study

Active, not recruitingNCT05465122

Mayo ClinicStenoses, Carotid

Start: 2022-07-05End: 2027-08-31Target: 2480Updated: 2026-05-28

EDAS Revascularization for Symptomatic Intracranial Atherosclerotic Steno-occlusive Disease

Not yet recruitingNCT07864649

Cedars-Sinai Medical CenterIntracranial Arterial Stenosis, Intracranial Atherosclerosis, Ischemic Stroke

Start: 2027-05-01End: 2031-11-30Target: 170Updated: 2026-10-22

Stroke Vascular and Interventional Neurology2026-06-23

Stenting versus medical treatment alone for symptomatic intracranial artery stenosis: a preplanned pooled individual patient data analysis.

2025-09-12

Estimated Theoretical Benefit of Aggressive LDL Lowering in Patients With Symptomatic Intracranial Atherosclerosis.

2025-05-30

Peri-procedural stroke or death in stenting of symptomatic severe intracranial stenosis

Journal of NeuroInterventional Surgery2019-09-0411 citations

Hemodynamic Markers in the Anterior Circulation as Predictors of Recurrent Stroke in Patients With Intracranial Stenosis

Stroke2018-12-24128 citations

Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A <sub>1c</sub> , LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study

JAMA2018-01-16284 citations

National Differences in Remission of Type 2 Diabetes Mellitus After Roux-en-Y Gastric Bypass Surgery-Subgroup Analysis of 2-Year Results of the Diabetes Surgery Study Comparing Taiwanese with Americans with Mild Obesity (BMI 30-35 kg/m<sup>2</sup>).

2017-05-0115 citations

Nonprocedural Symptomatic Infarction and In-Stent Restenosis After Intracranial Angioplasty and Stenting in the SAMMPRIS Trial (Stenting and Aggressive Medical Management for the Prevention of Recurrent Stroke in Intracranial Stenosis)

Stroke2017-04-2980 citations

Relationship between risk factor control and vascular events in the SAMMPRIS trial

Neurology2016-12-24189 citations

Factors Associated With Recurrent Ischemic Stroke in the Medical Group of the SAMMPRIS Trial

JAMA Neurology2016-01-1273 citations

Frequency, Risk Factors, and Outcome of Coexistent Small Vessel Disease and Intracranial Arterial Stenosis

JAMA Neurology2015-11-3062 citations

Does the Stenting Versus Aggressive Medical Therapy Trial Support Stenting for Subgroups With Intracranial Stenosis?

Stroke2015-09-1836 citations

Do Patient Characteristics Explain the Differences in Outcome Between Medically Treated Patients in SAMMPRIS and WASID?

2015-08-0628 citations

Roux-en-Y gastric bypass for diabetes (the Diabetes Surgery Study): 2-year outcomes of a 5-year, randomised, controlled trial.

2015-05-12139 citations

Outcome in Patients Previously on Antithrombotic Therapy in the SAMMPRIS Trial

Stroke2015-01-1621 citations

Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia

JAMA2013-06-05729 citations

Detailed analysis of periprocedural strokes in patients undergoing intracranial stenting in Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS).

2012-09-13150 citations

Stenting versus aggressive medical therapy for intracranial arterial stenosis.

2011-09-071312 citations

Intensive medical management

Sponsors

Conditions

Phase 3

Unknown Phase

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