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Inflectra 100 mg powder for concentrate for solution for infusion

DRUG13 trials

Sponsors

AstraZeneca AB, UZ Leuven, Astrazeneca AB, Region Skane, Centre Hospitalier Universitaire Amiens Picardie

Conditions

Acute severe ulcerative colitisAdvanced Biliary Tract CancersAdvanced Hepatocellular CarcinomaAdvanced Non-Small Cell Lung CancerAdvanced hepatocellular carcinoma (HCC)Advanced or Metastatic Non-Small Cell Lung CancerCrohn´s diseaseEarly-stage (II to IIIB) Non-small Cell Lung Cancer

Phase 2

Phase 3

A Phase IIIb Single Arm, Open-label, Multicentre Study of Durvalumab and Tremelimumab as First Line Treatment in Participants with Advanced Hepatocellular Carcinoma (SIERRA)
Active, not recruitingCTIS2022-502012-37-00
AstraZeneca ABAdvanced Hepatocellular Carcinoma
Start: 2023-10-06Target: 89Updated: 2025-10-14
A Phase IIIb, Single Arm, Open-label, Multicentre Study of Durvalumab in Combination with Chemotherapy for the First Line Treatment for Patients with Advanced Biliary Tract Cancers (TOURMALINE)
WithdrawnCTIS2022-502043-35-00
AstraZeneca ABAdvanced Biliary Tract Cancers
Target: 76Updated: 2023-09-04
A Phase III, Open-label, Randomised, Multicentre Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Without Actionable Genomic Alterations, and Whose Disease Has Progressed On or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy: LATIFY
Active, not recruitingCTIS2023-509429-37-00
AstraZeneca ABAdvanced or Metastatic Non-Small Cell Lung Cancer
Start: 2022-10-03Target: 520Updated: 2025-08-29
A Phase IIIb, Single Arm, Open-label, Multicentre Study of Durvalumab in Combination with Chemotherapy for the First Line Treatment for Patients with Advanced Biliary Tract Cancers (TOURMALINE)
Active, not recruitingCTIS2022-502043-35-01
AstraZeneca ABAdvanced Biliary Tract Cancers
Start: 2024-04-24Target: 76Updated: 2025-11-26
A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN).
Active, not recruitingCTIS2023-506413-22-00
Astrazeneca ABLocally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Start: 2021-03-31Target: 48Updated: 2026-01-09
A Randomized, Open-label, Multi-center Phase III Study of Durvalumab and Tremelimumab as First-line Treatment in Patients with advanced Hepatocellular Carcinoma (HIMALAYA)
Active, not recruitingCTIS2024-512212-21-00
AstraZeneca ABAdvanced hepatocellular carcinoma (HCC)
Start: 2017-11-28Target: 302Updated: 2025-12-16
IMPACT OF ANTI-TNF, VEDOLIZUMAB AND TOFACITINIB ON AORTIC STIFFNESS, CAROTID INTIMA-MEDIA THICKNESS AND CARDIOVASCULAR RISK OF PATIENTS WITH ULCERATIVE COLITIS
Not yet recruitingCTIS2024-517314-15-00
Centre Hospitalier Universitaire Amiens Picardieulcerative colitis
Target: 100Updated: 2024-09-10

Phase 4