Hypoglossal nerve stimulation

DEVICE6 trials

Sponsors

University of Pennsylvania, LivaNova, Invicta Medical Inc., Inspire Medical Systems, Inc., University Hospital, Antwerp

Conditions

ApneaApnea+HypopneaApnea, ObstructiveApnea, Obstructive SleepCardiovascular (CV) RiskDown Syndrome (DS)Hypopnea, SleepOSA

Unknown Phase

Mechanisms of Upper Airway Obstruction

CompletedNCT04322097

University of PennsylvaniaObstructive Sleep Apnea

Start: 2020-06-03End: 2024-05-10Updated: 2026-01-21

Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

CompletedNCT04950894

LivaNovaApnea, Apnea+Hypopnea, Apnea, Obstructive +4

Start: 2022-02-24End: 2025-04-23Updated: 2026-07-17

Evaluation of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea

CompletedNCT06283030

Invicta Medical Inc.Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes +1

Start: 2022-01-14End: 2023-05-31Updated: 2026-06-08

Evaluation of the Effects of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea

CompletedNCT06283017

Invicta Medical Inc.Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes +1

Start: 2022-04-06End: 2024-02-27Updated: 2026-06-08

Pediatric Down Syndrome Post-Approval Study

RecruitingNCT06851338

Inspire Medical Systems, Inc.Down Syndrome (DS), Pediatric Obstructive Sleep Apnea

Start: 2025-02-28End: 2030-05-31Target: 60Updated: 2025-02-28

Prospective Evaluation of New Metrics to Assess Cardiovascular Remodeling in Obstructive Sleep Apnea

RecruitingNCT07427589

University Hospital, AntwerpCardiovascular (CV) Risk, Obstructive Sleep Apnea

Start: 2026-06-10End: 2029-12-01Target: 270Updated: 2026-06-29

Related Papers

Proximal Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea in the OSPREY Study : A Randomized Controlled Trial.

2026-04-21