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HMS5552

DRUG11 trials

Sponsors

Hua Medicine Limited, Majianhua

Conditions

Diabetes Mellitus, Type 2Healthy SubjectType 2 DiabetesType 2 Diabetes MellitusType II Diabetes MellitusType2 Diabetes Mellitus

Phase 1

A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral HMS5552 in Healthy Volunteers
CompletedNCT01952535
Hua Medicine LimitedType II Diabetes Mellitus
Start: 2013-09-30End: 2013-12-31Updated: 2017-11-20
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HMS5552 in Patients With Type 2 Diabetes
CompletedNCT02077452
Hua Medicine LimitedType 2 Diabetes Mellitus
Start: 2014-03-31End: 2014-10-31Updated: 2017-11-20
Beta Cell Function and Related Pharmacodynamics of HMS5552 in T2DM Patients
CompletedNCT02386982
Hua Medicine LimitedType 2 Diabetes
Start: 2015-03-31End: 2015-05-31Updated: 2015-05-14
Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM
CompletedNCT02597400
Hua Medicine LimitedType 2 Diabetes Mellitus
Start: 2015-10-31End: 2015-10-31Updated: 2016-02-17
Human Mass Balance Study of HMS5552 in Healthy Subjects
CompletedNCT03158506
Hua Medicine LimitedHealthy Subject
Start: 2017-03-29End: 2017-04-06Updated: 2018-12-31
A Clinical Study to Access the Pharmacokinetics of HMS5552 in Renal Impaired Subjects and Healthy Volunteers
CompletedNCT04324424
Hua Medicine LimitedType 2 Diabetes Mellitus
Start: 2019-04-23End: 2019-09-30Updated: 2020-03-27
A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers
CompletedNCT04426708
Hua Medicine LimitedType 2 Diabetes Mellitus
Start: 2019-02-18End: 2020-07-03Updated: 2022-11-29

Phase 2

A Multi-center 12-week Study of HMS5552 in T2DM
CompletedNCT02561338
Hua Medicine LimitedDiabetes Mellitus, Type 2
Start: 2015-09-30End: 2016-09-30Updated: 2020-03-10

Phase 3

Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects
CompletedNCT03141073
Hua Medicine LimitedDiabetes Mellitus, Type 2
Start: 2017-10-15End: 2021-02-28Updated: 2021-08-26
Long-term Efficacy and Safety of HMS5552 in T2DM Subjects
CompletedNCT03173391
Hua Medicine LimitedDiabetes Mellitus, Type 2
Start: 2017-07-18End: 2020-11-30Updated: 2021-08-26

Unknown Phase

The Progress of Diabetes Mellitus After HMS5552 Treatment in Type 2 Diabetes Mellitus
NCT04091854
MajianhuaType2 Diabetes Mellitus
Start: 2018-12-12End: 2022-03-31Updated: 2021-08-26

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