HLA antibody

DIAGNOSTIC_TEST2 trials

Sponsors

University of Alberta

Conditions

Heart Transplant RejectionKidney Transplant Rejection

Unknown Phase

Trifecta-Kidney cfDNA-MMDx Study

RecruitingNCT04239703

University of AlbertaKidney Transplant Rejection

Start: 2019-12-01End: 2029-12-01Target: 300Updated: 2026-06-02

Trifecta-Heart cfDNA-MMDx Study

RecruitingNCT04707872

University of AlbertaHeart Transplant Rejection

Start: 2021-06-01End: 2028-07-01Target: 300Updated: 2026-06-02

Related Papers

A Two-Threshold dd-cfDNA Algorithm Improves Detection of Molecular Rejection in Heart Transplantation.

2026-06-22

Defining the relationships among four tests for assessing antibody-mediated rejection in heart transplants in a prospective, observational study.

2025-11-132 citations

Improving the histologic detection of donor-specific antibody-negative antibody-mediated rejection in kidney transplants

American Journal of Transplantation2025-08-233 citations

Defining Relationships Among Tests for Kidney Transplant Antibody-Mediated Rejection.

2025-06-172 citations

A cross-sectional study of the role of epithelial cell injury in kidney transplant outcomes.

2025-04-15

Comparing Plasma Donor–derived Cell-free DNA to Gene Expression in Endomyocardial Biopsies in the Trifecta-Heart Study

Transplantation2024-03-2817 citations

Distinct Molecular Processes Mediate Donor-derived Cell-free DNA Release From Kidney Transplants in Different Disease States

Transplantation2023-12-2719 citations

Antibody-mediated Rejection Without Detectable Donor-specific Antibody Releases Donor-derived Cell-free DNA: Results From the Trifecta Study

Transplantation2022-10-0358 citations

427.4: Combining Donor Derived Cell-Free DNA Fraction and Quantity To Detect Kidney Transplant Rejection Using Molecular Diagnoses

Transplantation2022-09-01

Combining Donor-derived Cell-free DNA Fraction and Quantity to Detect Kidney Transplant Rejection Using Molecular Diagnoses and Histology as Confirmation

Transplantation2022-06-2954 citations

The Trifecta Study: Comparing Plasma Levels of Donor-derived Cell-Free DNA with the Molecular Phenotype of Kidney Transplant Biopsies

Journal of the American Society of Nephrology2022-01-20113 citations