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High Intensity Focused Ultrasound

DEVICE20 trials

Sponsors

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's, SonaCare Medical, Philips Healthcare, Chongqing Medical University, Oxford University Hospitals NHS Trust

Conditions

Adenomyosis of UterusBCCBDBPHBPH (Benign Prostatic Hyperplasia)Bladder Outlet ObstructionBlue Rubber Bleb Nevus SyndromeBowen's Disease

Phase 1

Pilot Study for Palliation of Pain in Bone Metastases by MR-HIFU
CompletedNCT01117246
Philips HealthcareSecondary Malignant Neoplasm of Bone
Start: 2010-05-31End: 2011-10-31Updated: 2012-02-20

Phase 2

Focal Therapy Using HIFU for Localised Prostate Cancer
NCT02016040
Jewish General HospitalProstate Cancer
Start: 2013-03-17End: 2017-11-30Updated: 2017-04-19

Phase 4

High Intensity Focused Ultrasound Ablation Virus Myomectomy to Treat Uterine Fibroids
NCT01239641
Chongqing Medical UniversityUterine Fibroid
Start: 2010-09-30End: 2013-07-31Target: 220Updated: 2010-11-15

Unknown Phase

Prostate Cancer Treatment Following Radiation Failure With High Intensity Focused Ultrasound (HIFU)
CompletedNCT00318240
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sProstate Cancer
Start: 2006-04-30End: 2009-04-30Updated: 2017-08-28
A Multicenter Clinical Study of the Sonablate®450 for the TreAtment of Locally Recurrent Prostate Cancer With HIFU (STAR Trial)
NCT00772317
SonaCare MedicalRecurrent Prostate Cancer
Start: 2008-07-31End: 2021-12-31Updated: 2019-04-10
High Intensity Focused Ultrasound (HIFU) for Parathyroid Adenoma
TerminatedNCT01291498
Oxford University Hospitals NHS TrustParathyroid Adenomas
Start: 2011-04-30End: 2013-06-30Updated: 2017-12-18
Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound
CompletedNCT02078011
David R. Brenin, MDBreast Fibroadenoma
Start: 2014-04-30End: 2017-10-01Updated: 2018-05-07
Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)
CompletedNCT03022695
University Hospital TuebingenBreast Fibroadenoma
Start: 2013-10-31End: 2015-12-31Updated: 2024-07-22
High Intensity Focused Ultrasound Guided by MRI as Thermic Destruction in Primitive Small Size Breast Cancer
WithdrawnNCT03126487
Centre Antoine LacassagneBreast Cancer
Start: 2017-04-25End: 2018-01-11Updated: 2018-01-29
A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy
Active, not recruitingNCT03417297
University of North Carolina, Chapel HillFocal Epilepsy With Secondary Generalization, Partial Seizures With Secondary Generalization
Start: 2018-04-24End: 2028-05-31Target: 10Updated: 2025-08-15
Exploring HIFU as a Treatment for Rectal and Other Pelvic Cancers
NCT03595722
Imperial College LondonCervical Cancer, Endometrial Cancer, Pelvic Cancer +2
Start: 2019-07-11End: 2022-08-28Target: 60Updated: 2019-08-15
Feasibility of HIFU for Management of Placenta Accreta (HIFU-ACCRETA)
WithdrawnNCT04003428
Hospices Civils de LyonPlacenta Accreta
Start: 2021-11-01End: 2023-09-04Updated: 2023-11-18
Effect Of High-Intensity Focused Ultrasound On Abdominal Skin Laxity Post Sleeve Gastrectomy
CompletedNCT05994079
Cairo UniversityGastrostomy, Skin Laxity
Start: 2022-06-20End: 2022-12-20Updated: 2023-08-16
Effect of HIFU on Sleep Quality Measures in Obese Doubled Chin Women
RecruitingNCT06217445
Cairo UniversityOBESITY
Start: 2024-01-06End: 2024-04-06Target: 60Updated: 2024-01-22
Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery
Active, not recruitingNCT06642051
SonablateBlue Rubber Bleb Nevus Syndrome, Chronic Venous Insufficiency, CVI, CLOVES Syndrome +3
Start: 2024-09-11End: 2028-02-01Target: 30Updated: 2026-02-19
High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction
Not yet recruitingNCT07194187
Icahn School of Medicine at Mount SinaiBladder Outlet Obstruction, BPH
Start: 2026-09-01End: 2029-06-30Target: 17Updated: 2026-08-10
High Intensity Focused Ultrasound vs. Cryotherapy in the Treatment of Basal Cell Carcinomas and Bowen's Disease in Adults
Not yet recruitingNCT07384078
Jussi SalonenBCC, BD, Bowen's Disease +2
Start: 2026-04-01End: 2032-12-31Target: 294Updated: 2026-02-03
Sonablate HIFU International Registry for PC & BPH Patients
RecruitingNCT07757490
SonablateBPH (Benign Prostatic Hyperplasia), Localized Prostate Cancer, Prostate Cancer; Benign Prostatic Hyperplasia
Start: 2015-01-01End: 2035-12-01Target: 10000Updated: 2026-08-13
Clinical Evaluation of Linear Z for Body Contouring
RecruitingNCT07802431
Jeisys Medical IncNon Invasive Body Contouring
Start: 2026-09-01End: 2026-12-31Target: 30Updated: 2026-09-03
The Efficacy of High-Intensity Focused Ultrasound Therapy on Adenomyosis
Not yet recruitingNCT07808034
Far Eastern Memorial HospitalAdenomyosis of Uterus
Start: 2026-09-16End: 2028-12-31Target: 20Updated: 2026-09-08