Hematopoietic stem cells

BIOLOGICAL4 trials

Sponsors

Nantes University Hospital, National Cancer Institute (NCI), Radboud Universitair Medisch Centrum, Academisch Medisch Centrum

Conditions

Cardiovascular diseaseCore Binding Factor Alpha SubunitsGraft Versus Host DiseaseHematologic MalignancyHematologic NeoplasmsLeukemiaLymphomafamilial hypercholesterolemia genetic elevated 'bad' cholesterol

Phase 2

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation

RecruitingNCT06252870

Nantes University HospitalGraft Versus Host Disease, Hematologic Malignancy

Start: 2024-07-18End: 2028-07-18Target: 82Updated: 2026-01-26

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not yet recruitingNCT07524530

National Cancer Institute (NCI)Core Binding Factor Alpha Subunits, Hematologic Neoplasms, Leukemia +1

Start: 2026-05-27End: 2036-06-01Target: 98Updated: 2026-05-22

Unknown Phase

Determination of phenotypic and epigenetic *trained immunity* characteristics of hematopoietic stem and progenitor cells in patients with established atherosclerosis, a proof-of-principle study

Active, not recruitingNL-OMON43290

Radboud Universitair Medisch CentrumCardiovascular disease

Start: 2017-07-20Target: 30Updated: 2024-02-28

To study the effect of LDL-cholesterol and LDL-cholesterol lowering on hematopoietic stem cells and circulating immune cells in familial hypercholesterolemia patients.

Active, not recruitingNL-OMON47323

Academisch Medisch Centrumfamilial hypercholesterolemia genetic elevated 'bad' cholesterol

Start: 2017-07-05Target: 50Updated: 2024-02-28