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DEVICE5 trials

Sponsors

Massachusetts Institute of Technology

Conditions

Alzheimer DementiaAlzheimer DiseaseAlzheimer Disease, Early OnsetAlzheimer Disease, Late OnsetAlzheimer'sAlzheimer's DiseaseAlzheimer's Disease (Incl Subtypes)Down Syndrome

Unknown Phase

High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease
Active, not recruitingNCT04042922
Massachusetts Institute of TechnologyAlzheimer Disease
Start: 2019-04-19End: 2027-04-30Target: 80Updated: 2024-10-01
Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease
Active, not recruitingNCT04055376
Massachusetts Institute of TechnologyAlzheimer Dementia, Alzheimer Disease
Start: 2019-08-14End: 2027-01-15Updated: 2026-05-26
Gamma Frequency Stimulation in Individuals With Down Syndrome
RecruitingNCT05196984
Massachusetts Institute of TechnologyDown Syndrome
Start: 2021-12-06End: 2026-12-31Target: 60Updated: 2026-03-31
High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease
RecruitingNCT05268887
Massachusetts Institute of TechnologyParkinson Disease
Start: 2022-02-09End: 2027-11-01Target: 40Updated: 2026-03-31
Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy
RecruitingNCT05655195
Massachusetts Institute of TechnologyAlzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset +3
Start: 2022-12-14End: 2026-09-01Target: 60Updated: 2026-03-30

Related Papers

Gamma sensory stimulation in mild Alzheimer's dementia: An open-label extension study.
2025-10-01
Time saved in activities of daily living and whole‐brain volume: Post hoc analysis of a randomized feasibility trial of gamma oscillation treatment in participants with mild or moderate Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions2025-04-011 citations
Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer’s disease
Nature Communications2022-12-1486 citations
Gamma frequency sensory stimulation in mild probable Alzheimer’s dementia patients: Results of feasibility and pilot studies
PLoS ONE2022-12-01194 citations