fotemustine

DRUG6 trials

Sponsors

European Organisation for Research and Treatment of Cancer - EORTC, Institut du Cancer de Montpellier - Val d'Aurelle, Hoffmann-La Roche, National Cancer Institute, Naples, Italian Network for Tumor Biotherapy Foundation

Conditions

Brain MetastasesGlioblastoma MultiformeIntraocular MelanomaMalignant MelanomaMelanoma (Skin)Metastatic CancerRecurrent Melanoma

Phase 2

Fotemustine in Treating Patients With Metastatic Melanoma

TerminatedNCT00560118

Institut du Cancer de Montpellier - Val d'AurelleMelanoma (Skin)

Start: 2003-08-08End: 2008-08-31Updated: 2025-02-14

A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic Melanoma

CompletedNCT01069627

Hoffmann-La RocheMalignant Melanoma

Start: 2006-12-31End: 2009-07-31Updated: 2018-12-06

A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma

CompletedNCT01474239

Hoffmann-La RocheGlioblastoma Multiforme

Start: 2011-11-30End: 2013-12-31Updated: 2016-03-15

Phase 3

Intravenous or Hepatic Arterial Infusion of Fotemustine in Treating Patients With Unresectable Liver Metastases From Eye Melanoma

TerminatedNCT00110123

European Organisation for Research and Treatment of Cancer - EORTCIntraocular Melanoma, Metastatic Cancer

Start: 2005-01-31Updated: 2012-09-24

Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma

CompletedNCT01359956

National Cancer Institute, NaplesMalignant Melanoma, Recurrent Melanoma

Start: 2002-04-30End: 2011-02-28Updated: 2023-04-11

A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis

Italian Network for Tumor Biotherapy FoundationBrain Metastases

Start: 2012-12-31End: 2020-01-31Target: 168Updated: 2015-06-02

Related Papers

Time to response (TTR) and early tumor shrinkage (ETS) in recurrent glioblastoma patients treated with bevacizumab: an exploratory analysis of the prospective randomized AVAREG (ML25739) phase II study.

Journal of Clinical Oncology2015-05-201 citations

Hepatic intra-arterial versus intravenous fotemustine in patients with liver metastases from uveal melanoma (EORTC 18021): a multicentric randomized trial.

2014-02-0799 citations

Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma.

2013-02-1318 citations

(18)F-fluorodeoxyglucose positron emission tomography/computed tomography and magnetic resonance imaging in patients with liver metastases from uveal melanoma: results from a pilot study.

2012-02-0128 citations