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Fludarabina Teva 25 mg/ml concentrado para solución para perfusión o inyección EFG

DRUG8 trials

Sponsors

Cellectis, Iovance Biotherapeutics Inc., Fundacio Institut D Investigacio Biomedica De Bellvitge IDIBELL, Vall D Hebron Institute Of Oncology, Cabaletta Bio Inc.

Conditions

Active Idiopathic Inflammatory Myopathy including dermatomyositisActive Systemic Lupus Erythematosus;Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by autoantibody production and abnormal B cell function. SLE presents with fluctuating severity and may cause tissue damage in a variety of organs over time. Lupus nephritis (LN) is a common severe manifestation of SLEAdvanced selected solid tumors: melanomaAdvanced solid tumorsMelanomaMetastatic Non-Small-Cell Lung CancerRelapsed or refractory B cell acute lymphoblastic leukaemiaRelapsed or refractory B-cell Non-Hodgkin lymphoma

Phase 1

Open-label dose-finding and dose-expansion study to evaluate the safety, expansion, persistence, and clinical activity of UCART20x22 in subjects with relapsed or refractory B-cell Non-Hodgkin Lymphoma (B-NHL)
RecruitingCTIS2022-501607-27-00
CellectisRelapsed or refractory B-cell Non-Hodgkin lymphoma
Start: 2026-01-06Target: 48Updated: 2026-01-08
An Open-Label, Multi-Centre, Phase Ib/II Study Evaluating the Safety and Efficacy of AUTO1, a CAR T Cell Treatment Targeting CD19, in Adult Patients with Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia.
Active, not recruitingCTIS2024-512903-38-00
Autolus LimitedRelapsed or refractory B cell acute lymphoblastic leukaemia
Start: 2021-12-01Target: 17Updated: 2025-12-17
A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Systemic Lupus Erythematosus
RecruitingCTIS2023-507613-10-01
Cabaletta Bio Inc.Active Systemic Lupus Erythematosus;Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by autoantibody production and abnormal B cell function. SLE presents with fluctuating severity and may cause tissue damage in a variety of organs over time. Lupus nephritis (LN) is a common severe manifestation of SLE, which can lead to significant morbidity and mortality.
Start: 2025-03-31Target: 6Updated: 2026-01-26
A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Idiopathic Inflammatory Myopathy or Active Juvenile Idiopathic Inflammatory Myopathy
Not yet recruitingCTIS2025-521145-24-01
Cabaletta Bio Inc.Active Idiopathic Inflammatory Myopathy including dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy or Juvenile Idiopathic Inflammatory Myopathy
Target: 13Updated: 2026-04-30

Phase 2

Phase 3

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