ferric citrate

DRUG19 trials

Sponsors

Hamano Takayuki, Keryx Biopharmaceuticals, Panion & BF Biotech Inc., Denver Nephrologists, P.C., Winthrop University Hospital

Conditions

AnemiaAnemia of Chronic Kidney DiseaseChronic InflammationChronic Kidney DiseaseChronic Kidney DiseasesESRDEnd Stage Renal DiseaseEnd-Stage Renal Disease

Phase 2

A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)

CompletedNCT00648167

Keryx BiopharmaceuticalsEnd-stage Renal Disease, Hyperphosphatemia

Start: 2008-03-31End: 2009-01-31Updated: 2017-04-04

Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on Dialysis

CompletedNCT01736397

Keryx BiopharmaceuticalsIron Deficiency, Iron Deficiency Anemia

Start: 2012-11-30End: 2013-12-31Updated: 2017-10-20

Ferric Citrate and Chronic Kidney Disease in Children

RecruitingNCT04741646

University of California, Los AngelesChronic Kidney Diseases

Start: 2022-06-17End: 2028-11-30Target: 160Updated: 2026-04-17

Phase 3

A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease

CompletedNCT01074125

Keryx BiopharmaceuticalsEnd-Stage Renal Disease, Hyperphosphatemia

Start: 2010-05-31End: 2010-11-30Updated: 2014-12-04

A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Effects of Ferric Citrate in Subjects With End Stage Renal Disease

CompletedNCT01503736

Panion & BF Biotech Inc.End Stage Renal Disease, ESRD, Hyperphosphatemia

Start: 2010-06-30Updated: 2020-01-13

A Long-Term Safety Extension Trial of Ferric Citrate in Patients With End-Stage Renal Disease (ESRD) on Dialysis

CompletedNCT01554982

Keryx BiopharmaceuticalsEnd Stage Renal Disease, ESRD, Hyperphosphatemia +2

Start: 2012-08-31End: 2014-08-31Updated: 2016-07-13

KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKD

CompletedNCT02268994

Keryx BiopharmaceuticalsAnemia of Chronic Kidney Disease

Start: 2014-10-31End: 2016-01-31Updated: 2018-03-22

Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D

CompletedNCT02492620

Denver Nephrologists, P.C.Chronic Kidney Disease, Hyperphosphatemia, Iron Deficiency Anemia +1

Start: 2015-03-31End: 2017-11-30Updated: 2018-08-01

Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis

CompletedNCT03984760

Panion & BF Biotech Inc.End Stage Renal Disease, ESRD, Hyperphosphatemia

Start: 2019-06-19End: 2021-02-20Updated: 2021-03-10

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

SuspendedNCT04523727

Keryx BiopharmaceuticalsHyperphosphatemia Related to Chronic Kidney Disease

Start: 2022-06-16End: 2027-10-01Target: 45Updated: 2026-06-22

PBF-1681 (Ferric Citrate) for the Treatment of IDA in Patients With NDD-CKD

CompletedNCT04543812

Panion & BF Biotech Inc.Anemia of Chronic Kidney Disease

Start: 2020-10-14End: 2022-12-16Updated: 2025-06-29

Study to Evaluate the Safety and Tolerability of KRX-0502 (Ferric Citrate) in Children With Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease

WithdrawnNCT04649411

Keryx BiopharmaceuticalsIron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease

Start: 2025-01-31End: 2027-03-31Updated: 2025-11-20

Phase 4

A Study of Ferric Citrate to Improve Inflammation and Lipid Levels

TerminatedNCT02661295

Winthrop University HospitalChronic Inflammation, End Stage Renal Disease, Hyperphosphatemia

Start: 2015-07-31End: 2018-03-15Updated: 2023-04-20

Ferric Citrate in ESRD Pilot Project

Active, not recruitingNCT03055598

Sreedhar MandayamChronic Kidney Diseases, End Stage Renal Disease

Start: 2017-05-11End: 2020-02-29Updated: 2019-04-17

Transition to Ferric Citrate Among Hemodialysis and Peritoneal Dialysis Patients

CompletedNCT03079869

Kaiser PermanenteHyperphosphatemia

Start: 2017-05-01End: 2019-09-14Updated: 2022-01-13

Assess the Safety and Efficacy of Nephoxil® in Subjects With End Stage Renal Disease (ESRD) on Dialysis

CompletedNCT03256838

Panion & BF Biotech Inc.End-stage Renal Disease, Hyperphosphatemia, Kidney Failure, Chronic +1

Start: 2017-04-12End: 2019-05-31Updated: 2020-01-13

Unknown Phase

Trial of a New Formulation of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease

CompletedNCT00967993

Keryx BiopharmaceuticalsEnd-stage Renal Disease, Hyperphosphatemia, Renal Failure Chronic Requiring Hemodialysis

Start: 2010-01-31End: 2010-05-31Updated: 2014-12-05

Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency

CompletedNCT02888171

University of Alabama at BirminghamAnemia, Chronic Kidney Disease, Iron Deficiency

Start: 2016-09-30End: 2019-03-30Updated: 2020-03-24

The effect of ferric citrate on heart failure

Active, not recruitingJPRN-jRCTs041220137

Hamano TakayukiHeart failure Heart failure

Start: 2023-10-24Target: 162Updated: 2026-06-29

Related Papers

Long-term safety and efficacy of ferric citrate in phosphate-lowering and iron-repletion effects among patients with on hemodialysis: A multicenter, open-label, Phase IV trial

PLoS ONE2022-03-036 citations

A review of ferric citrate clinical studies, and the rationale and design of the Ferric Citrate and Chronic Kidney Disease in Children (FIT4KiD) trial.

2022-03-026 citations

Effect of Ferric Citrate versus Ferrous Sulfate on Iron and Phosphate Parameters in Patients with Iron Deficiency and CKD

Clinical Journal of the American Society of Nephrology2020-07-2126 citations