Fecal Microbiota Transplant (FMT)

BIOLOGICAL18 trials

Sponsors

Massachusetts General Hospital, Stacy A. Kahn, Boston Medical Center, Emory University, University of Alberta

Conditions

ADHDADHD - Attention Deficit Disorder With HyperactivityADHD - Combined TypeAcute Myeloid LeukemiaAllogeneic Hematopoietic Cell TransplantationChronic PouchitisClear Cell Renal Cell CarcinomaClostridium Difficile

Early Phase 1

Epigenetic and Microbiota Modifications

CompletedNCT05076656

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludDiabetes type2, Obesity

Start: 2019-06-10End: 2022-06-30Updated: 2022-07-22

Fecal Microbiota Transplant for Patients With Chronic Pouchitis

RecruitingNCT05829109

Maia KayalChronic Pouchitis, Pouchitis

Start: 2024-10-03End: 2027-09-01Target: 16Updated: 2026-08-17

Phase 1

Fecal Microbiota Transplant (FMT) for Relapsing C. Difficile Infection in Adults and Children Using a Frozen Inoculum

CompletedNCT01704937

Massachusetts General HospitalClostridium Difficile Infection

Start: 2012-11-30End: 2014-05-31Target: 20Updated: 2014-06-20

Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis

CompletedNCT02330653

Stacy A. KahnCrohn Disease, Inflammatory Bowel Diseases, Ulcerative Colitis

Start: 2015-11-30End: 2019-04-08Updated: 2023-10-16

Early FMT for C.Difficile

CompletedNCT02465463

Emory UniversityClostridium Difficile

Start: 2015-06-30End: 2016-11-30Updated: 2018-01-31

FMT for MDRO Colonization After Infection in Renal Transplant Recipients

TerminatedNCT02922816

Emory UniversityInfection Due to Resistant Organism

Start: 2016-12-01End: 2021-12-03Updated: 2023-11-15

Fecal Microbiota Transplantation (FMT) in Metastatic Melanoma Patients Who Failed Immunotherapy

Sheba Medical CenterMelanoma Stage Iv, Unresectable Stage III Melanoma

Start: 2017-11-30End: 2021-12-30Target: 40Updated: 2019-04-03

Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).

RecruitingNCT05664113

St. Jude Children's Research HospitalGastro-Intestinal Disorder

Start: 2025-07-07End: 2028-12-31Target: 10Updated: 2026-07-20

Phase 2

Prevention of Recurrence of Crohn's Disease by Fecal Microbiota Therapy (FMT)

TerminatedNCT02417974

Boston Medical CenterCrohn's Disease

Start: 2015-09-30End: 2021-02-04Updated: 2022-03-24

Fecal Transplant for Crohn's Disease

CompletedNCT03078803

University of AlbertaCrohn Disease

Start: 2017-03-28End: 2022-08-29Updated: 2022-09-07

A Study of FMT in Patients With AML Allo HSCT in Recipients

CompletedNCT03678493

Masonic Cancer Center, University of MinnesotaAcute Myeloid Leukemia, Allogeneic Hematopoietic Cell Transplantation

Start: 2019-09-09End: 2023-12-04Updated: 2024-05-16

Safety and Efficacy of Human Microbiota Transplantation for Overweight and Obese Type 2 Diabetes Mellitus

RecruitingNCT05253768

Zhujiang HospitalOverweight and Obesity, Type 2 Diabetes Mellitus

Start: 2024-03-31End: 2025-12-31Target: 39Updated: 2024-03-15

Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders

Active, not recruitingNCT05286294

Oslo University HospitalClear Cell Renal Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma +3

Start: 2022-06-28End: 2034-12-31Target: 20Updated: 2025-07-03

A Clinical Trial Evaluating Fecal Microbiota Transplantation (FMT) in Adolescents With ADHD

Not yet recruitingNCT07756255

University of CalgaryADHD, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type

Start: 2026-08-31End: 2029-08-31Target: 64Updated: 2026-09-10

Unknown Phase

Screening Donors, Fecal Microbiota Transplant Program in Ulcerative Colitis

RecruitingNCT04926103

Hamilton Health Sciences CorporationUlcerative Colitis Flare

Start: 2022-07-01End: 2029-05-01Target: 200Updated: 2024-10-01

Fecal Microbiota Transplantation for Preventing Gastrointestinal Symptoms in Extrapulmonary Neuroendocrine Neoplasms: A Real-World Study

Not yet recruitingNCT06924645

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityExtrapulmonary Neuroendocrine Neoplasms, Treatment-related Gastrointestinal Toxicity (Including Diarrhea, Constipation, Nausea, and Vomiting)

Start: 2025-05-01End: 2028-12-31Target: 40Updated: 2025-04-11

The Safety and Efficacy of Fecal Microbiota Transplant (FMT) for Steroid-refractory Graft-versus-host Disease

CompletedNCT06938165

Nanfang Hospital, Southern Medical UniversityGVHD

Start: 2020-04-27End: 2024-06-30Updated: 2025-04-22

Clinical Study on Fecal Microbiota Transplantation for Diarrhea After Total Pancreatectomy

Not yet recruitingNCT06960122

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityDiarrhea, Pancreatic Cancer, Resected

Start: 2025-05-01End: 2028-12-31Target: 10Updated: 2025-05-07

Related Papers

Safety and efficacy of fecal microbiota transplantation in solid cancers resistant to immune checkpoint inhibitors: results of the MITRIC trial.

2026-07-20

Fecal microbiota transplantation for refractory chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation: a pilot open-label, non-placebo-controlled study.

2025-08-262 citations

431. Engraftment of donor derived anaerobic taxa and durable long-term multidrug resistant organism decolonization following fecal microbiota transplantation

Open Forum Infectious Diseases2025-01-29

291. A Longitudinal Study of The Effect of Fecal Microbiota Transplantation on <i>Klebsiella pneumoniae</i> and its Bacteriophages in a Patient with Long-Term Colonization

Open Forum Infectious Diseases2023-11-271 citations

Dynamics of Fecal Antibiotic-Resistance Genes after Fecal Microbiota Transplantation in Allogeneic Hematopoietic Cell Transplant Recipients and AML Patients: Results from a Randomized Placebo-Controlled Trial

Blood2023-11-02

Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement

Science Translational Medicine2023-11-0194 citations

Abstract CT042: Fecal microbiota transplantation (FMT) and re-induction of anti-PD-1 therapy in refractory metastatic melanoma patients - preliminary results from a phase I clinical trial (NCT03353402)

Cancer Research2019-07-0115 citations

Abstract CT042: Fecal microbiota transplantation (FMT) and re-induction of anti-PD-1 therapy in refractory metastatic melanoma patients - preliminary results from a phase I clinical trial (NCT03353402)

Clinical Trials2019-07-013 citations

Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study

Clinical Infectious Diseases2014-04-23475 citations