EYP001a
Sponsors
Enyo Pharma, ENYO Pharma SAS, Enyo Pharma, SA
Conditions
HealthyHepatitis B
Chronic HBVHepatitis B
Hepatitis B
viral infection of the liver.Hepatitis B, ChronicNASH - Nonalcoholic Steatohepatitis
Phase 1
Study Evaluating Safety, Tolerability and Pharmacokinetics of EYP001a in Healthy Male Subjects
CompletedNCT03110276
Start: 2016-08-31End: 2017-03-31Updated: 2017-04-13
Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjects
CompletedNCT03272009
Start: 2017-09-21End: 2018-07-30Updated: 2018-08-21
EYP001a Food Effect Study in Subjects With Chronic Hepatitis B Virus (HBV) Infection
CompletedNCT03320616
Start: 2017-02-10End: 2017-10-12Updated: 2018-03-05
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EYP001a in Healthy Volunteers and Nonalcoholic Steatohepatitis Patients
CompletedNCT03976687
Start: 2019-06-11End: 2020-05-25Updated: 2020-09-25
Phase 2
A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir
CompletedNCT04365933
Start: 2020-05-25End: 2021-11-29Updated: 2022-08-25
Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)
TerminatedNCT04465916
Start: 2020-05-12End: 2021-11-25Updated: 2022-11-02
Unknown Phase
A phase 1, randomized, double-blind, placebo-controlled, escalating single- and multiple-dose study to evaluate the safety, tolerability and pharmacokinetics of EYP001a in healthy male subjects.
Active, not recruitingNL-OMON42859
Start: 2016-08-30Target: 96Updated: 2024-02-28
A randomized, double-blind, placebo-controlled study to determine the safety, tolerability, pharmacokinetics and pharmacodynamics of the FXR-agonist EYP001a in chronically HBV infected
subjects.
Active, not recruitingNL-OMON46529
Start: 2017-09-05Target: 18Updated: 2024-02-28