Ex Vivo-Expanded Cord Blood Progenitor Cell Infusion

BIOLOGICAL3 trials

Sponsors

Nohla Therapeutics, Inc., M.D. Anderson Cancer Center

Conditions

Accelerated Phase Chronic Myelogenous LeukemiaAcute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)

Phase 1

Donor Cord Blood T-Cell Infusion After Stem Cell Transplant in Treating Patients With Relapsed Hematological Malignancies

TerminatedNCT01630564

M.D. Anderson Cancer CenterHematopoietic and Lymphoid Cell Neoplasm

Start: 2013-03-11End: 2018-05-30Updated: 2018-11-13

Phase 2

Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies

CompletedNCT01175785

Nohla Therapeutics, Inc.Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities +17

Start: 2010-08-31End: 2014-08-31Updated: 2019-03-05

Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

CompletedNCT01690520

Nohla Therapeutics, Inc.Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission +2

Start: 2012-12-11End: 2020-05-29Updated: 2021-07-06

Related Papers

Infusion of Non-HLA-Matched Off-the-Shelf Ex Vivo Expanded Cord Blood Progenitors in Patients Undergoing Cord Blood Transplantation: Result of a Phase II Clinical Trial

Frontiers in Cell and Developmental Biology2022-04-047 citations