Epclusa

DRUG11 trials

Conditions

Bone Diseases, MetabolicBuprenorphine DependenceCardiovascular DiseasesCo-infectionCryoglobulinemiaDiabetes MellitusDrug UseEnd Stage Renal Disease

Phase 1

Expanding the Pool in Lung Transplantation

CompletedNCT03377478

Pablo SanchezHepatitis C, Lung Transplant

Start: 2019-07-30End: 2022-04-01Updated: 2022-12-16

Transplanting Hepatitis C Lungs Into Negative Lung Recipients

CompletedNCT03724149

University of PennsylvaniaLung Diseases

Start: 2018-12-12End: 2022-12-31Updated: 2023-04-14

Phase 2

Efficacy of All-Oral Anti-Viral Therapy for Symptomatic Hepatitis C Virus Infection-Related Cryoglobulinemia

CompletedNCT02825212

Icahn School of Medicine at Mount SinaiCryoglobulinemia, Hepatitis C

Start: 2016-02-29End: 2019-07-19Updated: 2020-12-17

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

RecruitingNCT03383419

Baylor Research InstituteHeart Failure

Start: 2018-03-20End: 2026-12-30Target: 15Updated: 2026-01-22

A Trial of Transplanting Hepatitis C Kidneys Into Hepatitis C-Negative Kidney Recipients

CompletedNCT04075916

University of PennsylvaniaEnd Stage Renal Disease

Start: 2021-06-22End: 2026-02-25Updated: 2026-03-12

Phase 3

Micro-elimination of Hepatitis C Virus Infection in Uremics

NCT03891550

Kaohsiung Medical University Chung-Ho Memorial HospitalHepatitis C

Start: 2019-05-13End: 2024-04-15Target: 135Updated: 2020-07-10

Phase 4

Lung Transplantation in Chronic HCV Infection With Post Transplant EPCLUSA Treatment

TerminatedNCT03207399

Duke UniversityHepatitis C, Chronic, Lung Transplant

Start: 2017-09-15End: 2019-03-25Updated: 2019-09-11

Bioequivalence study of CRUshed Sofosbuvir/velpAtasvir compareD to the wholE tablet (CRUSADE-1)/Hep-NED004

Active, not recruitingNL-OMON45504

Afdeling ApotheekHepatitis C

Start: 2017-12-01Target: 11Updated: 2024-02-28

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Active, not recruitingNCT03520660

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Cardiovascular Diseases, Diabetes Mellitus, Hepatitis C, Chronic

Start: 2018-10-19End: 2032-12-31Updated: 2026-03-24

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

NCT03549312

Saskatchewan Health Authority - Regina AreaBone Diseases, Metabolic, Buprenorphine Dependence, Co-infection +6

Start: 2018-02-01End: 2021-06-22Target: 25Updated: 2019-12-24

Unknown Phase

Eliminating HCV Infection Among PWUD

NCT05474781

Vancouver Infectious Diseases CentreDrug Use, Hepatitis C, Chronic

Start: 2019-02-22End: 2024-12-31Target: 300Updated: 2022-07-26

Open Forum Infectious Diseases2025-01-291 citations

P-2020. Combination Therapy with Remdesivir and Corticosteroids is Associated with Lower Mortality Risk vs. Corticosteroids Monotherapy in Patients Hospitalised for COVID-19

Open Forum Infectious Diseases2025-01-29

Efficacy and Safety of Remdesivir in People With Impaired Kidney Function Hospitalized for COVID-19 Pneumonia: A Randomized Clinical Trial

Clinical Infectious Diseases2024-06-2412 citations

Therapy as prevention toward HCV elimination in maintenance hemodialysis: a multi-center, prospective cohort study.

PubMed2023-12-011 citations

The SHELTER Trial of Transplanting Hepatitis C Virus–Infected Lungs Into Uninfected Recipients

Transplantation Direct2023-06-28

Consistent Effects of Early Remdesivir on Symptoms and Disease Progression Across At-Risk Outpatient Subgroups: Treatment Effect Heterogeneity in PINETREE Study

Infectious Diseases and Therapy2023-04-0111 citations

LB1. Remdesivir for the Treatment of High-Risk Non-Hospitalized Individuals With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Trial

Open Forum Infectious Diseases2021-11-018 citations

38. Remdesivir Treatment in Patients Hospitalized with COVID-19: A Comparative Analysis of In-Hospital All-Cause Mortality

Open Forum Infectious Diseases2021-11-01

A Randomized, Placebo-Controlled Clinical Trial of Bamlanivimab and Etesevimab Together in High-Risk Ambulatory Patients With COVID-19 and Validation of the Prognostic Value of Persistently High Viral Load

Clinical Infectious Diseases2021-10-2768 citations

Establishment of an outreach, grouping healthcare system to achieve microelimination of HCV for uremic patients in haemodialysis centres (ERASE-C)

Gut2020-12-1037 citations