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Endoxan

DRUG11 trials

Sponsors

Celgene Corp., Iovance Biotherapeutics Inc., F. Hoffmann-La Roche AG, NSABP Foundation Inc., Universitaire Ziekenhuizen KU Leuven

Conditions

ANCA Associated VasculitisAcute Myeloid LeukemiaBreast CancerChronic Lymphocytic Leukemia (CLL)ElderlyLupus NephritisLymphoma, T-Cell, PeripheralMelanoma

Phase 1

Phase 2

Phase 3

Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis
NCT03942887
Leiden University Medical CenterANCA Associated Vasculitis
Start: 2019-05-03End: 2025-04-01Target: 100Updated: 2023-12-14
A Randomized, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Idecabtagene Vicleucel with Lenalidomide Maintenance Versus Lenalidomide Maintenance Therapy Alone in Adult Participants with Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Active, not recruitingCTIS2022-501346-30-00
Celgene Corp.Newly Diagnosed Multiple Myeloma with Suboptimal Response After Autologous Stem Cell Transplantation
Start: 2023-09-25Target: 332Updated: 2025-12-09
A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy with Atezolizumab or Placebo in Patients with Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo "GeparDouze"
CompletedCTIS2023-508472-11-00
NSABP Foundation Inc.Patients with early breast cancer
Start: 2018-06-13End: 2025-11-19Target: 978Updated: 2025-08-05
A Phase 3, multicenter, randomized, open-label, parallel group, treatment study to assess the efficacy and safety of the lifileucel (LN-144, autologous tumor-infiltrating lymphocytes [TIL]) regimen in combination with pembrolizumab compared with pembrolizumab monotherapy in participants with untreated, unresectable or metastatic melanoma
RecruitingCTIS2022-503140-41-00
Iovance Biotherapeutics Inc.Melanoma
Start: 2024-11-29Target: 280Updated: 2025-10-31
A Prospective, Open-Label, Multicenter Randomized Phase III Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine and Rituximab (BR) in FIT Patients with previously untreated Chronic Lymphocytic Leukemia (CLL) without DEL(17P) or TP53 Mutation
CompletedCTIS2023-504036-17-00
F. Hoffmann-La Roche AGChronic Lymphocytic Leukemia (CLL)
Start: 2020-05-07End: 2025-03-18Target: 121Updated: 2025-04-17

Unknown Phase

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