Endoxan
Sponsors
Celgene Corp., Iovance Biotherapeutics Inc., F. Hoffmann-La Roche AG, NSABP Foundation Inc., Universitaire Ziekenhuizen KU Leuven
Conditions
ANCA Associated VasculitisAcute Myeloid LeukemiaBreast CancerChronic Lymphocytic Leukemia (CLL)ElderlyLupus NephritisLymphoma, T-Cell, PeripheralMelanoma
Phase 1
Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02
RecruitingNCT04167696
Start: 2019-11-25End: 2035-02-28Target: 27Updated: 2020-06-09
Safety, Activity and Cell Kinetics of CYAD-211 in Patients With Relapsed or Refractory Multiple Myeloma
Active, not recruitingNCT04613557
Start: 2020-11-16End: 2037-02-28Updated: 2023-08-31
Phase 2
Caelyx Adjuvant in Elderly Breast Cancer
CompletedNCT00284336
Start: 2006-01-31End: 2007-04-30Target: 16Updated: 2014-12-09
Brentuximab Vedotin in Combination With CHEP in Patient With PTCL
NCT05006664
Start: 2021-10-31End: 2024-10-31Target: 33Updated: 2021-09-01
A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Metastatic Non-Small-Cell Lung Cancer
RecruitingCTIS2024-510778-26-00
Start: 2025-12-19Target: 115Updated: 2025-11-26
Phase 3
Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis
NCT03942887
Start: 2019-05-03End: 2025-04-01Target: 100Updated: 2023-12-14
A Randomized, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Idecabtagene Vicleucel with Lenalidomide Maintenance Versus Lenalidomide Maintenance Therapy Alone in Adult Participants with Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Active, not recruitingCTIS2022-501346-30-00
Start: 2023-09-25Target: 332Updated: 2025-12-09
A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy with Atezolizumab or Placebo in Patients with Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo "GeparDouze"
CompletedCTIS2023-508472-11-00
Start: 2018-06-13End: 2025-11-19Target: 978Updated: 2025-08-05
A Phase 3, multicenter, randomized, open-label, parallel group, treatment study to assess the efficacy and safety of the lifileucel (LN-144, autologous tumor-infiltrating lymphocytes [TIL]) regimen in combination with pembrolizumab compared with pembrolizumab monotherapy in participants with untreated, unresectable or metastatic melanoma
RecruitingCTIS2022-503140-41-00
Start: 2024-11-29Target: 280Updated: 2025-10-31
A Prospective, Open-Label, Multicenter Randomized Phase III Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine and Rituximab (BR) in FIT Patients with previously untreated Chronic Lymphocytic Leukemia (CLL) without DEL(17P) or TP53 Mutation
CompletedCTIS2023-504036-17-00
Start: 2020-05-07End: 2025-03-18Target: 121Updated: 2025-04-17