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Emtricitabine/tenofovir disoproxil fumarate placebo
DRUG
3 trials
Sponsors
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
, National Institute of Allergy and Infectious Diseases (NIAID)
Conditions
HIV Infections
Phase 2
Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women
Completed
NCT00705679
National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Start: 2009-08-31
End: 2012-08-31
Updated: 2021-10-29
Phase 3
Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
Completed
NCT00118898
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Infections
Start: 2005-09-30
End: 2009-11-30
Updated: 2018-10-12
Unknown Phase
Bone Mineral Density Substudy - An Ancillary Study to MTN-003
Completed
NCT00729573
National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Start: 2009-11-30
End: 2013-05-31
Updated: 2023-02-08
Related Papers
Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202
Antimicrobial Agents and Chemotherapy
2019-01-14
16 citations
Sharing of Investigational Drug Among Participants in the Voice Trial.
2016-11-01
2 citations
Stated product formulation preferences for HIV pre‐exposure prophylaxis among women in the VOICE‐D (MTN‐003D) study
Journal of the International AIDS Society
2016-01-01
84 citations
Divergent adherence estimates with pharmacokinetic and behavioural measures in the MTN‐003 (VOICE) study
Journal of the International AIDS Society
2016-01-01
52 citations
Risk of HIV-1 acquisition among women who use diff erent types of injectable progestin contraception in South Africa: a prospective cohort study.
2015-07-01
43 citations
Pharmacological Measures of Treatment Adherence and Risk of HIV Infection in the VOICE Study
The Journal of Infectious Diseases
2015-06-29
43 citations
Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women
New England Journal of Medicine
2015-02-04
1278 citations
Association between efavirenz as initial therapy for HIV-1 infection and increased risk for suicidal ideation or attempted or completed suicide: an analysis of trial data.
2014-07-01
147 citations
Outcomes by sex following treatment initiation with atazanavir plus ritonavir or efavirenz with abacavir/lamivudine or tenofovir/emtricitabine.
2013-11-18
25 citations
Changes in fat mitochondrial DNA and function in subjects randomized to abacavir-lamivudine or tenofovir DF-emtricitabine with atazanavir-ritonavir or efavirenz: AIDS Clinical Trials Group study A5224s, substudy of A5202.
2012-11-29
50 citations
HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status.
2012-11-12
18 citations
A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel.
2011-10-19
87 citations
Peripheral and central fat changes in subjects randomized to abacavir-lamivudine or tenofovir-emtricitabine with atazanavir-ritonavir or efavirenz: ACTG Study A5224s.
2011-07-01
99 citations
Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: Aids Clinical Trials Group A5224s, a substudy of ACTG A5202.
2011-06-01
367 citations
Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.
2011-02-14
241 citations
Abacavir-lamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy.
2009-12-01
224 citations