E2006

DRUG6 trials

Sponsors

Eisai Inc.

Conditions

AdultsCNSChronic InsomniaElderlyHealthy SubjectsInsomniaMetabolism and Excretion

Phase 1

2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects

CompletedNCT01673451

Start: 2012-08-31End: 2013-07-31Updated: 2013-10-11

Open-Label Study of Bioavailability of E2006 Tablet Versus Capsule Formulations

CompletedNCT01673880

Eisai Inc.Insomnia

Start: 2012-08-31End: 2012-12-31Updated: 2013-05-22

An Open-label, Single-dose Study to Determine the Metabolism and Excretion of [14C]E2006 in Healthy Male Subjects

CompletedNCT02046213

Eisai Inc.Metabolism and Excretion

Start: 2014-02-28End: 2014-05-31Updated: 2015-11-03

A 2-Part Study to Assess Potential Metabolism-Based Drug-Drug Interactions of E2006 When Coadministered With Itraconazole, Rifampin, Midazolam, or Bupropion

CompletedNCT02085967

Eisai Inc.Healthy Subjects

Start: 2014-02-28End: 2014-06-30Updated: 2015-11-03

A Study to Determine the Effect of a High-Fat Meal on the Rate and Extent of E2006 Absorption in Healthy Subjects

CompletedNCT02089412

Eisai Inc.Healthy Subjects

Start: 2014-02-28End: 2014-06-30Updated: 2015-11-03

Phase 2

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia

CompletedNCT01995838

Eisai Inc.Adults, Chronic Insomnia, Elderly

Start: 2013-11-13End: 2014-04-29Updated: 2020-01-31

Related Papers

0453 Lemborexant Exposure Is Independent of Race

SLEEP2022-05-25

Lemborexant, A Dual Orexin Receptor Antagonist (DORA) for the Treatment of Insomnia Disorder: Results From a Bayesian, Adaptive, Randomized, Double-Blind, Placebo-Controlled Study.

2017-11-15106 citations