donor lymphocytes

BIOLOGICAL12 trials

Sponsors

Fred Hutchinson Cancer Center, Cancer and Leukemia Group B, Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium, Roswell Park Cancer Institute, Cancer Research UK

Conditions

Acute Myeloid LeukemiaAcute Myeloid Leukemia With Myelodysplasia Related Disease and < 30% BlastsAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Monoblastic Leukemia (M5a)Adult Acute Monocytic Leukemia (M5b)

Phase 1

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

CompletedNCT00006251

Fred Hutchinson Cancer CenterAcute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma +61

Start: 2000-05-31Updated: 2020-01-21

Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood

CompletedNCT00923910

National Cancer Institute (NCI)Leukemia, Acute Lymphocytic (ALL), Leukemia, Acute Myelogenous (AML), Leukemia, Chronic Myelogenous (CML) +2

Start: 2008-02-22End: 2016-11-15Updated: 2017-04-12

Phase 2

Reduced Intensity Donor Stem Cell Transplant in Treating Patients With High Risk Acute Lymphocytic Leukemia in Complete Remission

CompletedNCT00031655

Fred Hutchinson Cancer Research Center/University of Washington Cancer ConsortiumAdult Acute Lymphoblastic Leukemia in Remission, Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Adult Acute Lymphoblastic Leukemia +1

Start: 2001-09-30End: 2012-11-30Target: 30Updated: 2012-12-07

Fludarabine and Cyclophosphamide Followed by Peripheral Stem Cell Transplant in Treating Patients With Leukemia or Lymphoma

CompletedNCT00006252

Cancer and Leukemia Group BLeukemia, Lymphoma

Start: 2001-02-28End: 2011-10-31Updated: 2016-07-18

Donor Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Cancer Research UKLymphoma

Start: 2008-11-30Target: 25Updated: 2013-08-02

Fludarabine Phosphate, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed Hodgkin Lymphoma

Cancer Research UKLymphoma

Start: 2009-07-31Target: 49Updated: 2013-08-02

Carmustine, Etoposide, Cytarabine, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Cancer Research UKLymphoma

Start: 2009-07-31Target: 47Updated: 2013-08-02

Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant

TerminatedNCT01118013

Alliance for Clinical Trials in OncologyLeukemia, Lymphoma, Lymphoproliferative Disorder +3

Start: 2010-12-31End: 2013-08-31Updated: 2017-03-24

Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant

CompletedNCT02684162

M.D. Anderson Cancer CenterAcute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome +2

Start: 2016-06-22End: 2024-10-08Updated: 2025-11-06

A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS

RecruitingNCT05788679

Karolinska University HospitalAcute Myeloid Leukemia With Myelodysplasia Related Disease and < 30% Blasts, Mixed Myelodysplastic/Myeloproliferative Disease, Myelodysplastic Syndromes

Start: 2022-11-22End: 2026-12-31Target: 200Updated: 2023-12-05

Unknown Phase

Donor Lymphocyte Infusion in Treating Patients With Recurrent or Persistent Hematologic Cancer After Donor Stem Cell Transplant

CompletedNCT00534118

Roswell Park Cancer InstituteLeukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm +1

Start: 2003-10-01End: 2018-07-26Updated: 2020-08-26

AML Therapy With Irradiated Allogeneic Cells

TerminatedNCT02105116

Rutgers, The State University of New JerseyAdult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a) +13

Start: 2014-02-28End: 2015-12-16Updated: 2021-08-24

Related Papers

Allogeneic hematopoietic cell transplantation with non-myeloablative conditioning for patients with hematologic malignancies: Improved outcomes over two decades

Haematologica2020-06-0435 citations

Allo-HSCT in transplant-naïve patients with Hodgkin lymphoma: a single-arm, multicenter study

Blood Advances2019-12-238 citations