Diethylcarbamazine

DRUG10 trials

Conditions

Filarial; InfestationFilariasisHIV InfectionHelminthiasisLoiasisLymphatic FilariasisMansonelliasisOnchocerciasis

Phase 2

Effect of Albendazole Dose on Treatment of Lymphatic Filariasis

CompletedNCT00511004

National Institute of Allergy and Infectious Diseases (NIAID)Lymphatic Filariasis

Start: 2007-07-31End: 2014-02-28Updated: 2015-08-31

Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis

CompletedNCT01111305

National Institute of Allergy and Infectious Diseases (NIAID)Loiasis

Start: 2010-04-30End: 2017-09-30Updated: 2022-01-27

Eval 3-Drug Therapy Diethylcarbamize, Albendazole and Ivermectin That Could Accelerate LF Elimination Outside of Africa

CompletedNCT01975441

University Hospitals Cleveland Medical CenterLymphatic Filariasis

Start: 2014-05-31End: 2018-06-30Updated: 2018-10-09

PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )

CompletedNCT03664063

Lihir Medical CentreLymphatic Filariasis, Trauma, Yaws

Start: 2018-09-01End: 2019-01-01Updated: 2019-02-28

Phase 3

Moxidectin for LF, Cote d'Ivoire (DOLF)

CompletedNCT04410406

Washington University School of MedicineLymphatic Filariasis

Start: 2020-08-20End: 2024-10-01Updated: 2026-01-29

Phase 4

Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis

CompletedNCT01593722

National Institute of Allergy and Infectious Diseases (NIAID)Loiasis

Start: 2012-04-30End: 2014-01-31Updated: 2016-11-09

Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection

CompletedNCT02005653

Indian Council of Medical ResearchFilarial; Infestation

Start: 2009-02-28End: 2013-08-31Updated: 2013-12-09

Unknown Phase

Host Response to Infection and Treatment in Filarial Diseases

RecruitingNCT00001230

National Institute of Allergy and Infectious Diseases (NIAID)Filariasis, Helminthiasis, Mansonelliasis +2

Start: 1991-03-15Target: 500Updated: 2026-08-17

Interaction Between HIV and Lymphatic Filariasis

CompletedNCT00295698

DBL -Institute for Health Research and DevelopmentHIV Infection, Lymphatic Filariasis

Start: 2001-08-31End: 2002-11-30Updated: 2006-02-24

Lymphatic Filariasis (LF) in Ivory Coast

CompletedNCT02974049

University Hospitals Cleveland Medical CenterLymphatic Filariasis

Start: 2015-01-31End: 2018-09-25Updated: 2022-04-21

2025-05-06

P-2150. Eosinophilia in Patients with Suspected Parasitic Infection: a Retrospective Analysis

Open Forum Infectious Diseases2025-01-29

Safety and tolerability of moxidectin and ivermectin combination treatments for lymphatic filariasis in Côte d’Ivoire: A randomized controlled superiority study

PLoS neglected tropical diseases2023-09-188 citations

Pharmacokinetics of Moxidectin combined with Albendazole or Albendazole plus Diethylcarbamazine for Bancroftian Filariasis

PLoS neglected tropical diseases2023-08-245 citations

Population pharmacokinetic model of ivermectin in mass drug administration against lymphatic filariasis

PLoS neglected tropical diseases2023-06-014 citations

A Novel, Highly Sensitive Nucleic Acid Amplification Test Assay for the Diagnosis of Loiasis and its Use for Detection of Circulating Cell-Free DNA

The Journal of Infectious Diseases2023-05-277 citations

Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection

PLoS neglected tropical diseases2022-04-27145 citations

Semiannual Treatment of Albendazole Alone is Efficacious for Treatment of Lymphatic Filariasis: A Randomized Open-label Trial in Cote d’Ivoire

Clinical Infectious Diseases2021-02-289 citations

Pharmacokinetic and safety study of co-administration of albendazole, diethylcarbamazine, Ivermectin and azithromycin for the integrated treatment of Neglected Tropical Diseases

Clinical Infectious Diseases2020-08-1812 citations

IL-10 and Its Related Superfamily Members IL-19 and IL-24 Provide Parallel/Redundant Immune-Modulation in <i>Loa loa</i> Infection

The Journal of Infectious Diseases2020-06-1213 citations

Infection-associated Immune Perturbations Resolve 1 Year Following Treatment for<i>Loa loa</i>

Clinical Infectious Diseases2020-02-1220 citations

Efficacy and Safety of a Single Dose of Ivermectin, Diethylcarbamazine, and Albendazole for Treatment of Lymphatic Filariasis in Côte d’Ivoire: An Open-label Randomized Controlled Trial

Clinical Infectious Diseases2019-10-2158 citations

A Trial of a Triple-Drug Treatment for Lymphatic Filariasis

New England Journal of Medicine2018-11-07178 citations

Posttreatment Reactions After Single-Dose Diethylcarbamazine or Ivermectin in Subjects With Loa loa Infection

Clinical Infectious Diseases2017-01-3040 citations

Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis

Clinical Infectious Diseases2015-10-20190 citations