Diazoxide

DRUG16 trials

Sponsors

Grill, Valdemar, M.D., Rijnstate Hospital, Radboud University Medical Center, Assistance Publique - Hôpitaux de Paris, Virginia Commonwealth University

Conditions

CraniopharyngiomasDepressionDiabetes Mellitus, Insulin-DependentDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Gastro-enteropancreatic Neuroendocrine TumorGlucose Metabolism DisordersGlucose Metabolism Disorders (Including Diabetes Mellitus)

Phase 1

Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?

TerminatedNCT02049385

National Institute of Mental Health (NIMH)Depression

Start: 2014-01-03End: 2016-07-21Updated: 2017-10-13

Phase 2

Diazoxide-Mediated Insulin Suppression in Hyperinsulinemic Obese Men

CompletedNCT00151684

Rijnstate HospitalHyperinsulinism, Obesity

Start: 2004-11-30Target: 25Updated: 2008-02-29

DZX Mediated Insulin Suppression in Obese Men

CompletedNCT00631033

Rijnstate HospitalObesity

Start: 2008-07-31End: 2011-12-31Updated: 2014-11-06

Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy

CompletedNCT00892073

The Hospital for Sick ChildrenHypothalamic Obesity

Start: 2006-05-31End: 2008-01-31Updated: 2017-11-17

Diazoxide In the Management Of Hypoglycemic Neonates

University of SaskatchewanHypoglycemia, Infant, Diabetic Mother, Infant, Large for Gestational Age +2

Start: 2009-10-31End: 2011-10-31Target: 100Updated: 2009-10-14

Regulation of Endogenous Glucose Production by Central KATP Channels

RecruitingNCT03540758

Meredith HawkinsGlucose, High Blood, Glucose Metabolism Disorders, Type 2 Diabetes Mellitus

Start: 2018-08-01End: 2027-04-30Target: 100Updated: 2025-04-01

Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide

TerminatedNCT03566511

Meredith HawkinsDiabetes Mellitus, Type 2, Glucose, High Blood, Glucose Metabolism Disorders (Including Diabetes Mellitus)

Start: 2018-06-12End: 2020-08-01Updated: 2025-05-31

The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients

WithdrawnNCT03685773

Albert Einstein College of MedicineDiabetes Mellitus, Type 2, Glucose, High Blood, Glucose Metabolism Disorders

Start: 2019-04-21End: 2023-04-21Updated: 2023-06-05

Phase 3

Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions

CompletedNCT00306683

Assistance Publique - Hôpitaux de ParisCraniopharyngiomas, Hypothalamic-pituitary Lesions

Start: 2006-04-30End: 2009-04-30Updated: 2011-02-18

Phase 4

Efficacy of Diazoxide in Type 1 Diabetes

CompletedNCT00131755

Grill, Valdemar, M.D.Diabetes Mellitus, Type 1

Start: 2005-02-28End: 2008-08-31Updated: 2011-07-18

Central Mechanisms That Regulate Glucose Metabolism in Humans

TerminatedNCT01028846

Meredith HawkinsGlucose, High Blood, Glucose Metabolism Disorders, Type 2 Diabetes

Start: 2006-11-02End: 2007-12-05Updated: 2025-05-16

Use of Diazoxide in Acute Hypoglycaemia

CompletedNCT01488136

University of DundeeType 1 Diabetes

Start: 2012-01-31End: 2013-03-31Updated: 2019-10-14

Pasireotide Treatment for Neuroendocrine Tumor

WithdrawnNCT02779257

University of Maryland, BaltimoreGastro-enteropancreatic Neuroendocrine Tumor

Start: 2016-04-30End: 2016-06-30Updated: 2022-03-04

Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF)

TerminatedNCT03608163

Albert Einstein College of MedicineDiabetes Mellitus, Type 1, Hypoglycemia, Hypoglycemia Unawareness

Start: 2019-01-08End: 2019-08-22Updated: 2025-09-11

Unknown Phase

Ischemic Injury and Ischemic Preconditioning in Diabetes

CompletedNCT00184821

Radboud University Medical CenterDiabetes Mellitus, Insulin-Dependent, Ischemia-Reperfusion Injury

Start: 2004-06-30End: 2005-05-31Target: 20Updated: 2007-04-05

Insulin and Polycystic Ovary Syndrome

CompletedNCT00683774

Virginia Commonwealth UniversityPCOS

Start: 2005-11-30End: 2008-12-31Updated: 2017-06-14

Related Papers

How many unpublished studies? ClinicalTrials.gov (n = 2614 studies): diabetes | Closed Studies | Interventional Studies | Phase 3, 4 | Search Date: Oct 27, 2014

Figshare2014-01-01

Improved resistance to ischemia and reperfusion, but impaired protection by ischemic preconditioning in patients with type 1 diabetes mellitus: a pilot study.

2012-10-1022 citations