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Dexdor 100 micrograms/ml concentrate for solution for infusion

DRUG6 trials

Sponsors

Algemeen ziekenhuis Rivierenland, Helsinki University Central Hospital, Ziekenhuis Oost Limburg, Institut De Recerca Biomedica De Lleida Fundacio Dr. Pifarre, Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I Sunyer

Conditions

Neurodegenerative disease; Delirium; Acute neurological diseaseObesityPatients aged 60 years or older undergoing major surgery (thoracoscopic lung resection surgery)Patients scheduled for shoulder operationsPostoperative delirium

Phase 2

Influence of Dexmedetomidine on the Human Glymphatic Cerebrospinal Fluid Flow, Neural Activity and Cerebral Blood Flow in Functional Magnetic Resonance Imaging (GlymphDex)
Not yet recruitingCTIS2023-507215-35-00
Helsinki University Central HospitalNeurodegenerative disease; Delirium; Acute neurological disease
Target: 20Updated: 2025-09-17

Phase 3

Comparison of different doses of perineural dexmedetomidine as adjuvans to ropivacaine 0,67% for interscalene plexus block in association with 10 mg intravenous dexamethasone: a single center, double blinded, randomised controlled trial.
WithdrawnCTIS2023-506062-31-00
Algemeen ziekenhuis RivierenlandPatients scheduled for shoulder operations
Target: 260Updated: 2023-08-16
Comparison of different doses of perineural dexmedetomidine as adjuvans to ropivacaine 0,67% for interscalene plexus block in association with 10 mg intravenous dexamethasone: a single center, double blinded, randomised controlled trial.
RecruitingCTIS2023-506062-31-01
Algemeen ziekenhuis RivierenlandPatients scheduled for shoulder operations
Start: 2024-01-02Target: 260Updated: 2023-11-09

Phase 4

The effect of nocturnal dexmedetomidine on postoperative sleep quality and fatigue after major surgery in elderly patients: DEXSLEEP study
RecruitingCTIS2023-510403-22-00
Ziekenhuis Oost LimburgPatients aged 60 years or older undergoing major surgery (thoracoscopic lung resection surgery)
Start: 2024-06-03Target: 102Updated: 2024-04-02
Opioid-Free General Anesthesia Compared to Opioid-Based General Anesthesia for the Reduction of Postoperative Nausea and Vomiting in Patients Undergoing Robotic Bariatric Surgery - ANGELO Study
RecruitingCTIS2025-521047-20-00
Institut De Recerca Biomedica De Lleida Fundacio Dr. PifarreObesity
Start: 2025-11-13Target: 64Updated: 2025-07-22
Incidence and severity of postoperative delirium associated with Dexmedetomidine sedation during femur osteosynthesis in the elderly population
Not yet recruitingCTIS2025-523070-16-00
Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I SunyerPostoperative delirium
Target: 80Updated: 2026-08-31