Dexdor 100 micrograms/ml concentrate for solution for infusion

DRUG5 trials

Sponsors

Algemeen ziekenhuis Rivierenland, Helsinki University Central Hospital, Ziekenhuis Oost Limburg, Institut De Recerca Biomedica De Lleida Fundacio Dr. Pifarre

Conditions

Neurodegenerative disease; Delirium; Acute neurological diseaseObesityPatients aged 60 years or older undergoing major surgery (thoracoscopic lung resection surgery)Patients scheduled for shoulder operations

Phase 2

Influence of Dexmedetomidine on the Human Glymphatic Cerebrospinal Fluid Flow, Neural Activity and Cerebral Blood Flow in Functional Magnetic Resonance Imaging (GlymphDex)

Not yet recruitingCTIS2023-507215-35-00

Helsinki University Central HospitalNeurodegenerative disease; Delirium; Acute neurological disease

Target: 20Updated: 2025-09-17

Phase 3

Comparison of different doses of perineural dexmedetomidine as adjuvans to ropivacaine 0,67% for interscalene plexus block in association with 10 mg intravenous dexamethasone: a single center, double blinded, randomised controlled trial.

WithdrawnCTIS2023-506062-31-00

Algemeen ziekenhuis RivierenlandPatients scheduled for shoulder operations

Target: 260Updated: 2023-08-16

Comparison of different doses of perineural dexmedetomidine as adjuvans to ropivacaine 0,67% for interscalene plexus block in association with 10 mg intravenous dexamethasone: a single center, double blinded, randomised controlled trial.

RecruitingCTIS2023-506062-31-01

Algemeen ziekenhuis RivierenlandPatients scheduled for shoulder operations

Start: 2024-01-02Target: 260Updated: 2023-11-09

Phase 4

The effect of nocturnal dexmedetomidine on postoperative sleep quality and fatigue after major surgery in elderly patients: DEXSLEEP study

RecruitingCTIS2023-510403-22-00

Ziekenhuis Oost LimburgPatients aged 60 years or older undergoing major surgery (thoracoscopic lung resection surgery)

Start: 2024-06-03Target: 102Updated: 2024-04-02

Opioid-Free General Anesthesia Compared to Opioid-Based General Anesthesia for the Reduction of Postoperative Nausea and Vomiting in Patients Undergoing Robotic Bariatric Surgery - ANGELO Study

RecruitingCTIS2025-521047-20-00

Institut De Recerca Biomedica De Lleida Fundacio Dr. PifarreObesity

Start: 2025-11-13Target: 64Updated: 2025-07-22