DBS

DEVICE17 trials

Sponsors

University Hospital, Bonn, Rennes University Hospital, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University Medical Center Groningen, Abbott Medical Devices

Conditions

Advanced Parkinson's DiseaseAlcohol Use DisorderAutism Spectrum DisorderBipolar DisorderCognitive DeficitDeep Brain StimulationDyskinetic Cerebral PalsyDystonia

Phase 1

Effects of Deep Brain Stimulation in Treatment Resistant Major Depression

CompletedNCT01095263

University Hospital, BonnMajor Depression

Start: 2011-04-30End: 2013-01-31Updated: 2018-08-06

Coordinated Reset Deep Brain Stimulation for Parkinson's Disease

Not yet recruitingNCT07340073

University of MinnesotaDeep Brain Stimulation, Parkinson's Disease (PD)

Start: 2026-10-10End: 2031-07-01Target: 24Updated: 2026-09-14

Phase 3

SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant Schizophrenia

Shanghai Mental Health CenterTreatment-resistant Schizophrenia

Start: 2020-12-31End: 2022-12-31Target: 162Updated: 2020-08-27

Unknown Phase

Deep Brain Stimulation in Patients With Chronic Treatment Resistant Depression

CompletedNCT01973478

Rennes University HospitalBipolar Disorder, Major Depressive Disorder, Recurrent Depressive Disorder

Start: 2014-06-03End: 2018-11-27Updated: 2019-12-27

Clinical Study for Adaptive Deep Brain Stimulation (aDBS)Controlled by Intracerebral Activity in Parkinson's Disease

Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoAdvanced Parkinson's Disease

Start: 2013-09-30End: 2015-09-30Target: 20Updated: 2014-06-03

Deep Brain Stimulation (DBS) of the Nucleus Basalis of Meynert (NbM) in Patients With Parkinson's Disease

University Medical Center GroningenCognitive Deficit

Start: 2016-05-31Target: 13Updated: 2016-05-05

Intraoperative Investigation of a Directional Lead and Local Field Potentials for the Optimization of Stimulation Efficacy

CompletedNCT03630302

Abbott Medical DevicesParkinson

Start: 2018-07-12End: 2020-01-31Updated: 2021-05-28

Deep Brain Stimulation in Children With Autism

CompletedNCT03982888

The Hospital for Sick ChildrenAutism Spectrum Disorder, Self-Injurious Behavior

Start: 2019-08-14End: 2024-01-31Updated: 2024-02-22

DBS and Respiration

RecruitingNCT04058457

University of OxfordParkinson Disease

Start: 2021-04-01End: 2026-09-21Target: 60Updated: 2025-03-27

Unilateral GPi vs Unilateral STN DBS in the Same Patient With PD

CompletedNCT04255719

Ruijin HospitalDeep Brain Stimulation, Globus Pallidus Interna, Parkinson Disease +1

Start: 2020-03-01End: 2021-03-02Updated: 2021-03-04

Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS)

RecruitingNCT04296097

University Hospital, GrenobleResistant to Therapeutic Failure, Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, With or Without Hearing Loss +1

Start: 2021-04-23End: 2026-10-31Target: 7Updated: 2024-12-16

Deep Brain Stimulation for Alcohol Use Disorder

CompletedNCT05522751

Khaled MoussawiAlcohol Use Disorder

Start: 2023-01-10End: 2024-05-20Updated: 2025-08-15

Aim 3 Particle Swarm Optimization PIGD

RecruitingNCT05934747

University of MinnesotaParkinson's Disease and Parkinsonism

Start: 2024-03-19End: 2030-01-05Target: 30Updated: 2026-05-08

Study on Brain Network Mechanism of Deep Brain Stimulation for Parkinson's Disease

Not yet recruitingNCT05959161

Tianjin Huanhu HospitalDeep Brain Stimulation, Non-motor Symptoms, Parkinson Disease

Start: 2023-08-01End: 2026-12-31Target: 100Updated: 2023-07-25

Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults

RecruitingNCT06122675

University of California, San FranciscoDyskinetic Cerebral Palsy, Dystonic Cerebral Palsy

Start: 2024-03-26End: 2029-03-31Target: 10Updated: 2026-06-05

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

RecruitingNCT07325175

Children's Hospital Medical Center, CincinnatiDeep Brain Stimulation, Dystonia, Motor Development +1

Start: 2026-09-01End: 2031-08-31Target: 75Updated: 2026-09-11

Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease

RecruitingNCT07376278

Hong Kong University of Science and TechnologyDeep Brain Stimulation, PARKINSON DISEASE (Disorder)

Start: 2026-02-05End: 2038-02-01Target: 30Updated: 2026-02-24

Related Papers

Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: long-term outcomes from a first-in-human pilot trial.

2026-06-22

Cerebellar DBS during fMRI: initial findings and simulation-informed thermal assessment.

2026-03-12

GR.6 Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: a phase I pilot trial

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques2025-06-01

Deep Brain Stimulation of the Nucleus Accumbens for Severe Self-Injurious Behavior in Children: A Phase I Pilot Trial.

2024-12-053 citations

Protocol for combined N-of-1 trials to assess cerebellar neurostimulation for movement disorders in children and young adults with dyskinetic cerebral palsy

BMC Neurology2024-04-294 citations

An open-label prospective pilot trial of nucleus accumbens deep brain stimulation for children with autism spectrum disorder and severe, refractory self-injurious behavior: study protocol.

2022-02-0210 citations