CS-1103

DRUG3 trials

Sponsors

Clear Scientific, Inc.

Conditions

Fentanyl OverdoseFentanyl PoisoningMethamphetamine AbuseMethamphetamine DisordersMethamphetamine IntoxicationSubstance Use Disorders

Phase 1

A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants

CompletedNCT06316973

Clear Scientific, Inc.Methamphetamine Abuse, Methamphetamine Intoxication, Substance Use Disorders

Start: 2024-02-07End: 2024-06-06Updated: 2025-11-10

Phase 2

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

RecruitingNCT06721494

Clear Scientific, Inc.Methamphetamine Abuse, Methamphetamine Disorders, Methamphetamine Intoxication

Start: 2026-02-05End: 2026-09-11Target: 40Updated: 2026-01-12

A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade

Not yet recruitingNCT07459166

Clear Scientific, Inc.Fentanyl Overdose, Fentanyl Poisoning

Start: 2026-04-01End: 2026-10-01Target: 16Updated: 2026-03-27