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cross-linked hyaluronic acid

DRUG5 trials

Sponsors

Taipei Medical University, Semikal Technology, Istanbul Medipol University Hospital, Cairo University, Mansoura University

Conditions

Facial AgingFacial Wrinkles and Rhytides ReductionHyaluronic AcidIntrabony Periodontal DefectKnee Osteoarthritis (Knee OA)Lip Augmentation and Correction of Perioral RhytidsMarionette LinesNasolabial Fold Correction

Phase 1

Adding Effect of Cross-linked Hyaluronic Acid to Microneedling After Coronally Advanced Flap in Isolated RT1 Recession
Not yet recruitingNCT07520539
Cairo UniversitySingle RT1 Gingival Recession With no Loss of Interproximal Attachment
Start: 2026-07-01End: 2026-12-01Target: 22Updated: 2026-04-15
Evaluation of NIPSA Using Alloplastic Bone Graft and Cross-Linked Hyaluronic Acid in theTreatment of Intrabony Defects
Not yet recruitingNCT07737678
Mansoura UniversityIntrabony Periodontal Defect, Periodontal Disease
Start: 2026-08-01End: 2027-03-01Target: 60Updated: 2026-08-04

Phase 4

Cross-linked and Non-cross-linked Hyaluronic Acid in Subdeltoid Bursitis
Not yet recruitingNCT06508125
Taipei Medical UniversityHyaluronic Acid, Subdeltoid Bursitis
Start: 2024-07-25End: 2024-12-31Target: 52Updated: 2024-07-19

Unknown Phase

Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
Active, not recruitingNCT07160777
Semikal TechnologyFacial Aging, Facial Wrinkles and Rhytides Reduction, Lip Augmentation and Correction of Perioral Rhytids +5
Start: 2024-11-01End: 2025-12-31Updated: 2025-09-08
Cross-linked Hyaluronic Acid in Knee Osteoarthritis
CompletedNCT07241442
Istanbul Medipol University HospitalKnee Osteoarthritis (Knee OA)
Start: 2021-01-02End: 2025-05-31Updated: 2026-02-27