Creon

DRUG13 trials

Sponsors

Abbott Products, Hospital Avicenne, Azidus Brasil, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, AbbVie

Conditions

Chronic PancreatitisCystic FibrosisCystic Fibrosis (CF)Exocrine Pancreatic Insufficiency (EPI)Exocrine Pancreatic Insufficiency in Subjects With Diabetes Mellitus Type 2Fibrosing ColonopathyHypoglycemiaPancreatic Insufficiency

Early Phase 1

Pancreatic Enzyme Replacement and Glucose Regulation in Type 1 Diabetes

CompletedNCT05266963

Vanderbilt University Medical CenterType 1 Diabetes

Start: 2022-09-02End: 2024-03-22Updated: 2025-03-28

Phase 1

CREON for the Treatment of Post-RYGB Hypoglycemia

TerminatedNCT02733848

East Carolina UniversityHypoglycemia

Start: 2014-02-28End: 2018-01-31Target: 5Updated: 2023-10-26

Phase 2

Clinical Non-Inferiority of Pancreatic Enzymes (Norzyme ® - Bergamo) Compared To Creon ® (Solvay Pharmaceutical) in Patients With Exocrine Pancreatic Insufficiency

Azidus BrasilPancreatic Insufficiency

Start: 2010-03-31End: 2011-06-30Target: 25Updated: 2010-10-28

Phase 2 Study to Assess the Safety and Efficacy of ANG003

RecruitingNCT07450547

Anagram Therapeutics, Inc.Cystic Fibrosis (CF), Exocrine Pancreatic Insufficiency (EPI)

Start: 2026-04-24End: 2027-07-01Target: 113Updated: 2026-08-27

Phase 4

Creon After Pancreatic Surgery

CompletedNCT00535756

Abbott ProductsPancreatic Insufficiency

Start: 2008-04-30End: 2011-06-30Updated: 2011-08-18

Evaluation of the Digestive and Metabolic Utilisation of Dietary Protein in Patients With Chronic Pancreatitis

CompletedNCT00957151

Hospital AvicenneChronic Pancreatitis

Start: 2004-04-30End: 2005-08-31Target: 12Updated: 2009-08-12

Creon Use in Coeliac Patients With Low Faecal Pancreatic Elastase

TerminatedNCT01865695

Sheffield Teaching Hospitals NHS Foundation TrustPatients With Coeliac Disease and Chronic Diarrhoea (>3 Loose/ Liquid Motions a Day for More Than 4 Weeks), Patients With Pancreatic Exocrine Insufficiency

Start: 2013-05-31End: 2014-08-31Updated: 2019-09-23

A Study to Assess the Effect of Creon® on Pancreatic Exocrine Insufficiency in Subjects With Diabetes Mellitus Type 2

WithdrawnNCT02009410

AbbottExocrine Pancreatic Insufficiency in Subjects With Diabetes Mellitus Type 2

Start: 2013-11-30End: 2014-08-31Updated: 2014-06-20

Study Of Effects Of Oral CREON Capsules In Adult Participants With Exocrine Pancreatic Insufficiency Not Due To Cystic Fibrosis, Chronic Pancreatitis, Pancreatectomy, Or Pancreatic Cancer

WithdrawnNCT04315311

AbbVieExocrine Pancreatic Insufficiency (EPI)

Start: 2020-05-06End: 2021-09-22Updated: 2021-11-08

Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or Chronic Pancreatitis Treated With Creon

CompletedNCT05069597

AbbVieChronic Pancreatitis, Cystic Fibrosis

Start: 2021-10-14End: 2023-08-28Updated: 2024-07-23

Unknown Phase

Effect of Enzyme Therapy on Protein Metabolism in Chronic Pancreatitis

CompletedNCT01154608

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementPancreatitis

Start: 2005-04-30Updated: 2025-10-06

Long-term Study in US Cystic Fibrosis Patients Receiving Digestive Enzyme Supplements to Assess Narrowing of the Large Intestine Causing Adverse Intestinal Symptoms (Fibrosing Colonopathy)

TerminatedNCT01652157

AbbVieFibrosing Colonopathy

Start: 2012-07-31End: 2020-04-08Updated: 2021-03-22

Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) Symptoms

CompletedNCT04949828

AbbVieChronic Pancreatitis

Start: 2021-09-16End: 2024-02-29Updated: 2024-03-28

Related Papers

Pancrelipase Improves Symptoms of Exocrine Pancreatic Insufficiency and Health-Related Quality of Life in a Real-World Population of Patients with Chronic Pancreatitis

Digestive Diseases and Sciences2026-05-13