Control toothpaste

DRUG9 trials

Sponsors

Lion Corporation, Colgate Palmolive, University of Aarhus, Sun Yat-sen University, Unilever R&D

Conditions

Dental PlaqueDental Plaque and GingivitisDentin HypersensitivityDentin hypersensitivity Chronic periodontitis Dentin hypersensitivity Root sensitivity Desensitizing agent Calcium sodium phosphosilicate Arginine and calcium carbonateGingival BleedingGingival InflammationGingivitisHypersensitivity

Phase 2

The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis

CompletedNCT02243046

Colgate PalmoliveDental Plaque and Gingivitis

Start: 2014-12-31End: 2015-05-31Updated: 2019-02-25

Comparison of efficacy of 5% calcium sodium phosphosilicate and 8% arginine and calcium carbonate in reducing dentin hypersensitivity following non-surgical periodontal therapy

Active, not recruitingTCTR20180611003

Faculty of Dentistry, Chulalongkorn UniversityDentin hypersensitivity Chronic periodontitis Dentin hypersensitivity Root sensitivity Desensitizing agent Calcium sodium phosphosilicate Arginine and calcium carbonate

Start: 2018-09-28Updated: 2026-03-30

Phase 3

Effects of Antioxidant Dentifrice on Gingivitis

CompletedNCT02102295

Lion CorporationGingivitis

Start: 2006-09-30End: 2007-07-31Updated: 2014-04-02

Clinical of Hypersensitivity Reduction Efficacy on Two Toothpastes

CompletedNCT06937697

Colgate PalmoliveHypersensitivity

Start: 2024-10-08End: 2024-12-13Updated: 2025-04-22

Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste

CompletedNCT06956599

Colgate PalmoliveDentin Hypersensitivity

Start: 2025-05-10End: 2025-08-11Updated: 2026-03-19

Unknown Phase

Investigation of the Instant Tooth Whitening Effect of a Silica Toothpaste Containing Blue Covarine

CompletedNCT03760367

University of AarhusTooth Whitening

Start: 2018-11-13End: 2018-11-23Updated: 2019-11-19

Whitening Efficacy of Dentifrice Containing 10% High Cleaning Silica, 0.5% Sodium Phytate and 0.5% Sodium Pyrophosphate

CompletedNCT04238429

Sun Yat-sen UniversityTooth Bleaching

Start: 2018-05-07End: 2018-10-05Updated: 2022-02-23

Evaluation of the Effect of Zinc Citrate Trihydrate Toothpaste on the Oral Plaque Microbiome

CompletedNCT06358742

Unilever R&DDental Plaque

Start: 2017-01-10End: 2017-05-19Updated: 2024-04-11

Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem

Not yet recruitingNCT07415733

Unilever R&DDental Plaque, Gingival Bleeding, Gingival Inflammation

Start: 2026-02-01End: 2026-08-01Target: 150Updated: 2026-02-17

Related Papers

Reduction of extrinsic tooth stain by a toothpaste containing 10% high cleaning silica, 0.5% sodium phytate and 0.5% sodium pyrophosphate: an 8-week randomised clinical trial.

2021-03-119 citations