Control group:Guideline-recommended standard of care, including atorvastatin, rosuvastatin, etc.

2 trials

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Conditions

Ischemic StrokeIschemic stroke

Phase 2

Evolocumab for ImproVing FunctiOnal Outcomes in ThromboLyzed Patients with Acute Ischemic Stroke without Large VEssel Occlusion: A Prospective, Multicenter, Randomized Controlled Trial (EVOLVE-Stroke I)

RecruitingChiCTR2600125072

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyIschemic Stroke

Start: 2026-05-21Updated: 2026-05-25

Unknown Phase

EVOLVE-Stroke II: Evolocumab Combined with EndoVascular Thrombectomy for Acute Ischemic Stroke with Large Vessel OccLusion: A Randomized Controlled Trial (EVOLVE-Stroke II)

Active, not recruitingChiCTR2600124661

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyIschemic stroke

Start: 2026-05-19Updated: 2026-05-18