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Consolidation Chemotherapy

DRUG9 trials

Sponsors

Hospital Israelita Albert Einstein, Wake Forest University Health Sciences, Jing Jin, M.D., State Scientific Centre of Coloproctology, Russian Federation, Alexandria University

Conditions

Acute Myeloid LeukemiaAcute Myeloid Leukemia (AML)ChemoradiotherapyChemotherapyChemotherapy Side EffectsLocally Advanced Rectal CarcinomaLow Anterior Resection SyndromeMyelodysplastic Syndromes

Phase 2

Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms
CompletedNCT02084563
Hospital Israelita Albert EinsteinAcute Myeloid Leukemia, Myelodysplastic Syndromes, Myeloproliferative/Myelodysplastic Neoplasm +1
Start: 2012-10-31End: 2016-11-30Updated: 2016-11-08
A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk
NCT04664504
Jing Jin, M.D.Rectal Cancer
Start: 2020-12-01End: 2025-12-01Target: 150Updated: 2021-06-08
Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer
CompletedNCT05274945
Alexandria UniversityRectal Cancer
Start: 2020-01-01End: 2022-01-01Updated: 2022-03-11
Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal Cancer
CompletedNCT05792735
Shenzhen People's HospitalLocally Advanced Rectal Carcinoma
Start: 2023-04-11End: 2025-01-31Updated: 2025-02-05
Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.
RecruitingNCT06758830
National Cancer Center Affiliate of Vilnius University Hospital Santaros KlinikosChemoradiotherapy, Chemotherapy, Chemotherapy Side Effects +8
Start: 2025-01-06End: 2029-12-27Target: 400Updated: 2026-05-11

Phase 3

Leukemia Stem Cell Detection in Acute Myeloid Leukemia
TerminatedNCT02927938
Wake Forest University Health SciencesAcute Myeloid Leukemia (AML)
Start: 2016-09-30End: 2018-10-05Updated: 2022-04-21

Phase 4

Total Neoadjuvant Therapy in Rectal Cancer Treatment
NCT04747951
State Scientific Centre of Coloproctology, Russian FederationRectal Cancer
Start: 2020-10-30End: 2023-11-01Target: 280Updated: 2021-02-15

Unknown Phase

Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial
RecruitingNCT05496491
Larissa University HospitalRectal Neoplasms
Start: 2022-08-30End: 2026-08-30Target: 84Updated: 2024-10-08
Adaptive Boost Radiotherapy to Primary Lesions and Positive Nodes in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer
SuspendedNCT06246344
Shandong Cancer Hospital and InstituteRectal Cancer
Start: 2023-12-01End: 2028-12-01Target: 128Updated: 2026-05-01

Related Papers

Short-course radiation(SCRT) followed by 6 cycles of cadonilimab plus mFOLFOX6 as neoadjuvant therapy for patients with locally advanced rectal cancer (LARC): A multicenter, single arm, phase II trial (NeoCaCRT).
Journal of Clinical Oncology2025-01-271 citations
Efficacy and safety of MR-guided adaptive simultaneous integrated boost radiotherapy to primary lesions and positive lymph nodes in the neoadjuvant treatment of locally advanced rectal cancer: a randomized controlled phase III trial
Radiation Oncology2024-09-122 citations
Effectiveness of the total neo-adjuvant therapy in rectal cancer treatment. Results of the randomized trial
Koloproktologia2024-02-271 citations
Safety of the total neo-adjuvant therapy in rectal cancer treatment. Preliminary results of the randomized trial
Koloproktologia2022-09-151 citations