Combined oral contraceptives

DRUG8 trials

Sponsors

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Omar Mamdouh Shaaban, University of Southern California, Women and Infants Hospital of Rhode Island, Cairo University

Conditions

Abnormal Uterine BleedingAbnormal Uterine Bleeding, Endometrial Hemostatic DysfunctionAbnormal Uterine Bleeding, Ovulatory DysfunctionAdenomyosisChlamydia InfectionHypothalamic-pituitary-ovarian Axis, Gonadotropins, Ethinyl Estradiol, Contraceptive EfficacyNeisseriaceae InfectionPremenstrual Syndrome

Phase 2

LNG-IUS for Treatment of Dysmenorrhea

CompletedNCT01601366

Omar Mamdouh ShaabanAdenomyosis

Start: 2012-04-30End: 2015-04-30Updated: 2017-11-22

Phase 3

Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in Severe Premenstrual Syndrome

Cairo UniversityPremenstrual Syndrome

Start: 2015-07-31Target: 300Updated: 2017-01-23

Does Adding Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome?

Cairo UniversityPremenstrual Syndrome

Start: 2015-10-31End: 2017-09-30Target: 300Updated: 2016-07-06

Hormone Replacement for Premature Ovarian Insufficiency

WithdrawnNCT02922348

University of PennsylvaniaPrimary Ovarian Insufficiency

Start: 2016-03-01End: 2018-12-01Updated: 2019-07-05

Unknown Phase

Hormonal Contraception and Risk of Chlamydia and Gonorrhea

TerminatedNCT00091728

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Chlamydia Infection, Neisseriaceae Infection

Start: 1997-09-30End: 2001-08-31Target: 1200Updated: 2005-11-07

Oral Contraceptive Hormone-free Interval Pituitary/ Ovarian Activity

CompletedNCT01953211

University of Southern CaliforniaHypothalamic-pituitary-ovarian Axis, Gonadotropins, Ethinyl Estradiol, Contraceptive Efficacy

Updated: 2019-07-26

Stopping Heavy Periods Project

Women and Infants Hospital of Rhode IslandAbnormal Uterine Bleeding, Abnormal Uterine Bleeding, Endometrial Hemostatic Dysfunction, Abnormal Uterine Bleeding, Ovulatory Dysfunction

Start: 2013-02-28End: 2021-12-31Target: 59Updated: 2021-08-02

A randomized controlled trial of two different regimen in the treatment of unfavourable vaginjal bleeding in women on etonogestrel implant

Active, not recruitingPACTR202508557960619

Ajayi Tejumademanagement of menstrual side-effects following use of subdermal contraceptive implants

Start: 2025-11-01Target: 70Updated: 2026-01-27