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Clavulanic Acid

DRUG6 trials

Sponsors

Assistance Publique Hopitaux De Paris, Temple University, University of Missouri-Columbia, University of Health Sciences Lahore

Conditions

Acute Otitis MediaCocaine AbuseCocaine Abuse, in RemissionCocaine AddictionCocaine DependenceCocaine Dependence, in RemissionCocaine-Related DisordersTobacco Use Disorder

Phase 1

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study
CompletedNCT02563769
Temple UniversityCocaine Abuse, Cocaine Addiction, Cocaine Dependence +1
Start: 2016-10-24End: 2018-05-25Updated: 2023-11-03
Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid
CompletedNCT03986762
Temple UniversityCocaine Abuse, in Remission, Cocaine Dependence, in Remission, Cocaine-Related Disorders
Start: 2019-03-12End: 2019-12-20Updated: 2020-10-26
Pharmaco-Magnetic Resonance Spectroscopy (MRS) Study of Clavulanic Acid
CompletedNCT04411914
Temple UniversityCocaine Dependence
Start: 2020-09-01End: 2022-03-31Updated: 2023-06-22

Phase 2

An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction
RecruitingNCT03713424
University of Missouri-ColumbiaTobacco Use Disorder
Start: 2019-03-26End: 2026-08-31Target: 30Updated: 2025-10-28
Acute non-severe osteomyelitis in children - Outpatient management strategy with oral antibiotic therapy compared to a standard strategy with conventional hospitalization and intravenous antibiotic therapy: randomized open-label non-inferiority study with Bayesian and medico-economic analyses.
Not yet recruitingCTIS2024-516744-26-00
Assistance Publique Hopitaux De Parisacute osteomyelitis of the child
Target: 320Updated: 2025-04-09

Unknown Phase

Comparison of Amoxicillin and Amoxicillin + Clavulanic Acid in Treating Acute Otitis Media in Children
Not yet recruitingNCT06895135
University of Health Sciences LahoreAcute Otitis Media
Start: 2025-05-31End: 2026-05-31Target: 162Updated: 2025-03-30

Related Papers

Clavulanic Acid Decreases Cocaine Cue Reactivity in Addiction-Related Brain Areas, a Randomized fMRI Pilot Study
Psychopharmacology Bulletin2025-08-122 citations