Cimetidine
Sponsors
Lytix Biopharma AS, Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd., Merck Sharp & Dohme LLC, Community Research Initiative of New England, Hoag Memorial Hospital Presbyterian
Conditions
Advanced or Metastatic Non-small Cell Lung CancerAdvanced MelanomaAnatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage IA Breast Cancer AJCC v8Anatomic Stage IB Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8
Phase 1
Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body
TerminatedNCT00800280
Start: 2009-01-31End: 2009-02-28Updated: 2010-02-17
Effect of Repeated Doses of BI 1060469 and BI 1021958 on Glomerular Filtration Rate (GFR) in Healthy Volunteers
CompletedNCT02202512
Start: 2014-09-30End: 2014-12-31Updated: 2014-12-24
This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men
CompletedNCT03307252
Start: 2017-10-25End: 2018-05-02Updated: 2023-11-07
Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects
CompletedNCT03380455
Start: 2018-01-09End: 2018-01-29Updated: 2022-06-02
Effect of Cimetidine on the PK of Imeglimin
CompletedNCT03618316
Start: 2018-06-19End: 2018-07-27Updated: 2018-08-27
Drug-drug Interaction Study of Gepotidacin
CompletedNCT04493931
Start: 2020-08-14End: 2020-12-21Updated: 2022-03-04
Phase 2
Biological Therapy in Treating Patients With Metastatic Cancer
CompletedNCT00002733
Start: 1996-01-31End: 2000-01-31Target: 30Updated: 2011-05-11
Papillary Serous Carcinoma of the Endometrium
CompletedNCT00515073
Start: 2001-04-30End: 2013-05-31Updated: 2014-07-03
Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel
CompletedNCT04862585
Start: 2021-10-07End: 2024-06-21Updated: 2025-08-20
Effect of Oral Cimetidine in the Protoporphyrias
CompletedNCT05020184
Start: 2022-06-14End: 2025-04-24Updated: 2026-01-21
A Phase 2 Study of Intratumoral Injection of LTX-315 in Combination with Pembrolizumab in Patients with Percutaneously Accessible Lesions with Advanced Melanoma Refractory to PD-1/PD-L1 Inhibitor Therapy
CompletedCTIS2022-500628-31-00
Start: 2022-10-24End: 2025-06-13Target: 22Updated: 2024-03-11
A Phase II Study of SKB264 as Monotherapy or as Combination Therapy in Subjects with Advanced or Metastatic Non-small Cell Lung Cancer
Active, not recruitingCTIS2023-507270-41-00
Start: 2024-11-22Target: 46Updated: 2025-07-29
A Phase I-II, First-in-Human Study of SKB264 in Patients with Locally Advanced Unresectable /Metastatic Solid Tumors Who are Refractory to Available Standard Therapies
CompletedCTIS2023-508700-38-00
End: 2024-12-10Target: 31Updated: 2024-06-20
Phase 3
High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer
CompletedNCT01757275
Start: 2013-02-28End: 2014-12-31Updated: 2016-03-08
Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients
CompletedNCT02157376
Start: 2014-07-31End: 2016-02-29Updated: 2017-03-10
The Efficacy of Cimetidin for Acute - Extrinsic Atopic Dermatitis Treated With Standard Therapy
NCT04018131
Start: 2018-03-26End: 2020-06-30Target: 26Updated: 2019-10-04
A Phase 3, Randomized, Open-label, Multicenter Study to Compare the Efficacy and Safety of Sacituzumab Tirumotecan in Combination with Pembrolizumab Versus Pembrolizumab Alone as First-line Maintenance Treatment in Participants with Mismatch Repair Proficient Endometrial Cancer (TroFuse-033/GOG-3119/ENGOT-en29)
RecruitingCTIS2024-519331-42-00
Start: 2025-08-22Target: 355Updated: 2025-10-28