Bosentan 125 mg

DRUG4 trials

Sponsors

Actelion, Geropharm, University of Mississippi Medical Center

Conditions

BioequivalenceDigital UlcersRacial DisparitySystemic SclerosisVascular Function

Early Phase 1

Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1

TerminatedNCT04770155

University of Mississippi Medical CenterRacial Disparity, Vascular Function

Start: 2021-05-27End: 2021-09-20Updated: 2023-10-31

Phase 1

Bioequivalence Study of Bosentan 125 mg Tablets Immediate Release (IR) Versus Tracleer® 125 mg Tablets IR In Healthy Subjects

CompletedNCT04101370

GeropharmBioequivalence

Start: 2018-05-24End: 2018-06-20Updated: 2019-09-24

Phase 3

Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma

CompletedNCT00077584

ActelionDigital Ulcers, Systemic Sclerosis

Start: 2003-10-31End: 2005-05-31Updated: 2025-02-03

Bosentan in Digital Ulcers

CompletedNCT00319696

ActelionDigital Ulcers

Start: 2004-07-08End: 2009-01-22Updated: 2025-02-04