Bezafibrate

DRUG13 trials

Sponsors

Rigshospitalet, Denmark, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Assistance Publique - Hôpitaux de Paris, Instituto Mexicano del Seguro Social, Newcastle-upon-Tyne Hospitals NHS Trust

Conditions

Acute Coronary SyndromeAcute Myocardial InfarctionAdrenomyeloneuropathyAtherosclerotic Cardiovascular DiseaseBipolar DisorderCarnitine Palmitoyltransferase II DeficiencyDepressive EpisodeHypercholesterolemia

Phase 2

Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects

CompletedNCT00983788

Rigshospitalet, DenmarkCarnitine Palmitoyltransferase II Deficiency, Very Long Chain Acyl Coa Dehydrogenase Deficiency

Start: 2009-10-31End: 2011-09-30Updated: 2012-05-30

A Study of Bezafibrate in Mitochondrial Myopathy

CompletedNCT02398201

Newcastle-upon-Tyne Hospitals NHS TrustMitochondrial Diseases

Start: 2015-09-30End: 2017-03-23Updated: 2017-09-21

BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study

RecruitingNCT02481245

Massachusetts General HospitalBipolar Disorder, Depressive Episode

Start: 2018-01-11End: 2026-02-28Target: 30Updated: 2025-10-03

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

TerminatedNCT04594694

Intercept PharmaceuticalsPrimary Biliary Cholangitis

Start: 2019-10-02End: 2025-10-14Updated: 2025-11-17

Phase 3

Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis

CompletedNCT01654731

Assistance Publique - Hôpitaux de ParisPBC

Start: 2012-10-15End: 2016-12-31Updated: 2023-02-27

Bezafibrate Plus Berberine in Mixed Dyslipidemia

CompletedNCT02548832

University of GuadalajaraMixed Dyslipidemia

Start: 2013-04-30End: 2020-04-01Updated: 2023-02-24

The Effect of Bezafibrate on Cholestatic Itch

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Primary Biliary Cholangitis, Primary Sclerosing Cholangitis, Secondary Sclerosing Cholangitis

Start: 2016-02-29End: 2018-04-30Target: 84Updated: 2016-03-08

Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-responders

Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranPrimary Biliary Cirrhosis

Start: 2016-10-31End: 2019-12-31Target: 34Updated: 2018-04-23

Phase 4

Bezafibrate for Hyperfibrinogenemia in Acute Myocardial Infarction

CompletedNCT02291796

Instituto Mexicano del Seguro SocialAcute Myocardial Infarction

Start: 2011-01-31End: 2013-12-31Updated: 2014-11-14

Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia

CompletedNCT02984982

SanofiAcute Coronary Syndrome, Hypercholesterolemia

Start: 2016-11-15End: 2018-07-27Updated: 2019-09-09

Unknown Phase

The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD)

CompletedNCT01165060

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Adrenomyeloneuropathy, X-linked Adrenoleukodystrophy

Start: 2010-07-31End: 2011-08-31Target: 10Updated: 2011-08-10

PC-300 Tea Effect on Triglyceride Levels

CompletedNCT03649269

Ciprés Grupo Médico CGM SCHypertriglyceridemia

Start: 2014-01-01End: 2014-12-31Updated: 2018-08-28

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

RecruitingNCT06858332

Novartis PharmaceuticalsAtherosclerotic Cardiovascular Disease

Start: 2025-04-15End: 2027-09-30Target: 2382Updated: 2025-08-03

Related Papers

A randomized, controlled trial on fenofibrate in primary biliary cholangitis patients with incomplete response to ursodeoxycholic acid

Therapeutic Advances in Chronic Disease2022-01-0131 citations

Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial.

2020-10-05128 citations

A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis

New England Journal of Medicine2018-06-06566 citations

Effect of alirocumab on coronary atheroma volume in Japanese patients with acute coronary syndromes and hypercholesterolemia not adequately controlled with statins: ODYSSEY J-IVUS rationale and design.

2018-03-307 citations

Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial.

2017-05-2315 citations

Bezafibrate for X-linked adrenoleukodystrophy.

2012-07-2020 citations