Betaine

DRUG18 trials

Sponsors

Mayo Clinic, University Hospital, Basel, Switzerland, University of California, San Diego, University of Nebraska, University of Sao Paulo

Conditions

Angelman SyndromeArsenic Metabolites Measured in UrineBetaine SupplementationBlood Flow Restriction TrainingBody Temperature ChangesBody Water DehydrationChronic Hepatitis CDysglycemia

Early Phase 1

Pilot Study of Betaine + Combination Antiviral Therapy for Chronic Hepatitis C Genotype 1 Non-responder/Relapsers

TerminatedNCT00882193

University of NebraskaChronic Hepatitis C, Genotype 1, Relapse

Start: 2009-05-01End: 2011-01-12Updated: 2023-11-30

Phase 1

Maternal Betaine Supplementation During Breastfeeding

Active, not recruitingNCT04633044

Fundació Sant Joan de DéuOverweight and Obesity

Start: 2021-02-11End: 2026-10-01Updated: 2026-03-24

Phase 2

Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria

CompletedNCT00283387

Mayo ClinicHyperoxaluria

Start: 2007-02-28End: 2011-09-30Updated: 2013-12-16

Chronic Hepatitis C Non-Responder Study With AdoMet and Betaine

CompletedNCT00310336

University Hospital, Basel, SwitzerlandHepatitis C

Start: 2006-08-31End: 2009-09-30Target: 30Updated: 2010-10-28

Metabolic Effects of Betaine Supplementation

CompletedNCT01950039

Joslin Diabetes CenterDysglycemia, Obesity

Start: 2014-01-31End: 2018-08-31Updated: 2021-04-20

Betaine METABOLISM OF PATIENTS With Homocystinuria

CompletedNCT02404337

Assistance Publique - Hôpitaux de ParisHomocystinuria

Start: 2015-07-31End: 2018-02-28Updated: 2023-02-03

The Therapeutic Effect of Betaine in Syringomyelia

RecruitingNCT06308367

Xuanwu Hospital, BeijingSyringomyelia

Start: 2024-03-31End: 2028-03-31Target: 30Updated: 2024-03-13

Betaine vs. Placebo for Serologically Diagnosed Metabolic Dysfunction-associated Steatohepatitis (MASH)

Not yet recruitingNCT07276204

Southern California Institute for Research and EducationMASH - Metabolic Dysfunction-Associated Steatohepatitis

Start: 2026-03-31End: 2035-12-31Target: 70Updated: 2026-01-08

Phase 3

Betaine and Peroxisome Biogenesis Disorders

CompletedNCT01838941

McGill University Health Centre/Research Institute of the McGill University Health CentrePeroxisome Biogenesis Disorders

Start: 2013-03-31End: 2015-06-30Updated: 2016-06-28

Phase 4

A Preliminary Study of Choline and Betaine Supplementation Among Adults Exposed to Arsenic in Bangladesh

CompletedNCT01749982

Columbia UniversityArsenic Metabolites Measured in Urine

Start: 2012-12-31End: 2014-08-31Updated: 2014-08-28

Unknown Phase

Dietary Supplements for the Treatment of Angelman Syndrome

CompletedNCT00348933

University of California, San DiegoAngelman Syndrome, Nervous System Diseases

Start: 2006-07-31End: 2010-02-28Updated: 2012-09-24

Effects of Betaine Supplementation on Strength and Muscle Creatine Content

CompletedNCT01213719

University of Sao PauloHealthy Subjects

Start: 2010-10-31End: 2011-07-31Updated: 2012-01-16

Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21

CompletedNCT02118142

UNC Nutrition Research InstituteInsulin Sensitivity

Start: 2014-03-31End: 2014-07-31Updated: 2014-08-12

The Effects of Pre-Loaded Betaine Supplementation on Thermoregulation and Exercise Metabolism in the Heat

CompletedNCT04585295

Florida State UniversityHealthy

Start: 2020-01-21End: 2023-12-15Updated: 2024-03-13

Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle

CompletedNCT05790070

Baylor UniversityBetaine Supplementation, Blood Flow Restriction Training

Start: 2021-02-01End: 2021-07-30Updated: 2023-03-29

Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

CompletedNCT06042270

Michael J. OrmsbeeBody Temperature Changes, Body Water Dehydration, Inflammation

Start: 2023-12-20End: 2024-09-01Updated: 2024-10-17

Betaine Supplementation and Lipid Metabolism in Overweight and Obese Pre-menopausal Women

CompletedNCT06344377

Poznan University of Life SciencesOverweight and Obesity

Start: 2024-09-01End: 2025-10-30Updated: 2025-11-24

Betaine, Exercise Performance, and Gut Permeability

CompletedNCT06392360

Appalachian State UniversityMetabolic Disturbance, Permeability; Increased

Start: 2024-08-13End: 2025-02-11Updated: 2025-03-11

Related Papers

Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial.

2022-11-144 citations

A placebo-controlled trial of folic acid and betaine in identical twins with Angelman syndrome.

2019-10-223 citations

S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse.

2010-11-0815 citations