Aztreonam
Sponsors
Micurx Pharmaceuticals Inc., Pfizer Inc., Uppsala Universitet, Assistance Publique Hopitaux De Paris, Centre Hospitalier Universitaire De Nimes
Conditions
Bacterial InfectionBlood Stream InfectionCRE ColonizationCarbapenem-resistant EnterobacteralesComplicated Skin and Soft Tissue InfectionCystic FibrosisDiabetic Foot InfectionsGonorrhea
Phase 1
Phase 2
Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure Infections
CompletedNCT00633152
Start: 2008-02-29End: 2008-07-31Updated: 2017-03-14
Aztreonam for Pharyngeal Gonorrhea
CompletedNCT03867734
Start: 2019-04-05End: 2019-09-30Updated: 2022-01-18
C3601008 - A PHASE 2A MULTICENTER, OBSERVER-BLINDED, RANDOMIZED 2 ARM STUDY TO INVESTIGATE PHARMACOKINETICS, SAFETY, TOLERABILITY AND EFFICACY OF INTRAVENOUS AZTREONAM-AVIBACTAM ± METRONIDAZOLE COMPARED TO BEST AVAILABLE THERAPY (BAT) IN PEDIATRIC PARTICIPANTS 9 MONTHS TO LESS THAN 18 YEARS OF AGE WITH SERIOUS GRAM-NEGATIVE BACTERIAL INFECTIONS INCLUDING COMPLICATED INTRA-ABDOMINAL INFECTION
RecruitingCTIS2022-501575-12-00
Start: 2023-04-24Target: 20Updated: 2025-10-15
Pivmecillinam as oral step-down treatment for Escherichia coli febrile urinary tract infection versus standard of care; a randomized controlled non-inferiority multicenter trial
RecruitingCTIS2023-503447-33-00
Start: 2025-11-13Target: 560Updated: 2025-10-08
Phase 3
Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections
CompletedNCT01499277
Start: 2012-05-31End: 2015-01-31Updated: 2017-09-06
Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections
CompletedNCT01811732
Start: 2013-04-30End: 2014-07-31Updated: 2017-09-27
Delafloxacin vs Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections
CompletedNCT01984684
Start: 2014-05-31End: 2016-01-31Updated: 2017-11-17
Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.
TerminatedNCT02202135
Start: 2014-06-30End: 2015-01-31Updated: 2017-09-06
Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)
CompletedNCT02276482
Start: 2015-03-25End: 2018-09-17Updated: 2019-08-07
A Phase 3, Multicenter, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults with Moderate or Severe Diabetic Foot Infections
RecruitingCTIS2022-500257-16-00
Start: 2023-03-17Target: 791Updated: 2025-07-15
COTRIVAP - Efficacy of cotrimoxazole as a de-escalation treatment of Ventilator-Associated Pneumonia in intensive care unit. Multicentric non-inferiority randomised controlled trial
CompletedCTIS2023-505108-52-00
Start: 2023-12-20End: 2025-09-19Target: 628Updated: 2025-04-23
Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase Producing Enterobacterales Undergoing Liver Transplantation
Not yet recruitingNCT07759453
Start: 2026-10-01End: 2029-09-30Target: 168Updated: 2026-08-12
FOSFOLD - Fosfomycin trometamol compared with another active antibiotic relay therapy for the treatment of acute Escherichia coli pyelonephritis in elderly women: a randomized, multicenter, non-inferiority trial
Not yet recruitingCTIS2025-521663-13-00
Target: 312Updated: 2026-08-21
Phase 4
Antibiotic Prophylaxis for Transrectal Prostate Biopsy
CompletedNCT01659866
Start: 2012-08-31End: 2016-08-31Updated: 2019-06-25
Aztreonam for Inhalation Solution (AZLI) for the Treatment of Exacerbations of Cystic Fibrosis
CompletedNCT02894684
Start: 2017-01-31End: 2019-09-30Updated: 2019-10-07
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study
to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
Not yet recruitingCTIS2024-516232-10-00
Target: 200Updated: 2025-10-17