Aztreonam
Sponsors
Micurx Pharmaceuticals Inc., Pfizer Inc., Uppsala Universitet, Assistance Publique Hopitaux De Paris, Centre Hospitalier Universitaire De Nimes
Conditions
Bacterial InfectionBlood Stream InfectionComplicated Skin and Soft Tissue InfectionCystic FibrosisDiabetic Foot InfectionsGonorrheaGonorrhea of PharynxHealthy Volunteers
Phase 1
Phase 2
Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure Infections
CompletedNCT00633152
Start: 2008-02-29End: 2008-07-31Updated: 2017-03-14
Aztreonam for Pharyngeal Gonorrhea
CompletedNCT03867734
Start: 2019-04-05End: 2019-09-30Updated: 2022-01-18
C3601008 - A PHASE 2A MULTICENTER, OBSERVER-BLINDED, RANDOMIZED 2 ARM STUDY TO INVESTIGATE PHARMACOKINETICS, SAFETY, TOLERABILITY AND EFFICACY OF INTRAVENOUS AZTREONAM-AVIBACTAM ± METRONIDAZOLE COMPARED TO BEST AVAILABLE THERAPY (BAT) IN PEDIATRIC PARTICIPANTS 9 MONTHS TO LESS THAN 18 YEARS OF AGE WITH SERIOUS GRAM-NEGATIVE BACTERIAL INFECTIONS INCLUDING COMPLICATED INTRA-ABDOMINAL INFECTION
RecruitingCTIS2022-501575-12-00
Start: 2023-04-24Target: 20Updated: 2025-10-15
Pivmecillinam as oral step-down treatment for Escherichia coli febrile urinary tract infection versus standard of care; a randomized controlled non-inferiority multicenter trial
RecruitingCTIS2023-503447-33-00
Start: 2025-11-13Target: 560Updated: 2025-10-08
Phase 3
Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections
CompletedNCT01499277
Start: 2012-05-31End: 2015-01-31Updated: 2017-09-06
Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections
CompletedNCT01811732
Start: 2013-04-30End: 2014-07-31Updated: 2017-09-27
Delafloxacin vs Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections
CompletedNCT01984684
Start: 2014-05-31End: 2016-01-31Updated: 2017-11-17
Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.
TerminatedNCT02202135
Start: 2014-06-30End: 2015-01-31Updated: 2017-09-06
Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)
CompletedNCT02276482
Start: 2015-03-25End: 2018-09-17Updated: 2019-08-07
A Phase 3, Multicenter, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults with Moderate or Severe Diabetic Foot Infections
RecruitingCTIS2022-500257-16-00
Start: 2023-03-17Target: 791Updated: 2025-07-15
COTRIVAP - Efficacy of cotrimoxazole as a de-escalation treatment of Ventilator-Associated Pneumonia in intensive care unit. Multicentric non-inferiority randomised controlled trial
CompletedCTIS2023-505108-52-00
Start: 2023-12-20End: 2025-09-19Target: 628Updated: 2025-04-23
Phase 4
Antibiotic Prophylaxis for Transrectal Prostate Biopsy
CompletedNCT01659866
Start: 2012-08-31End: 2016-08-31Updated: 2019-06-25
Aztreonam for Inhalation Solution (AZLI) for the Treatment of Exacerbations of Cystic Fibrosis
CompletedNCT02894684
Start: 2017-01-31End: 2019-09-30Updated: 2019-10-07
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study
to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
Not yet recruitingCTIS2024-516232-10-00
Target: 200Updated: 2025-10-17