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AZD6234

DRUG10 trials

Sponsors

AstraZeneca AB, AstraZeneca

Conditions

Diabetes, Type IIEndocrinologyHealthy ParticipantsInvestigating obesity or overweight condition correlated to many co-morbiditiesObesityObesity or OverweightObesity/OverweightOverweight and obesity

Phase 1

Assess the Safety, Tolerability, and Pharmacokinetics of AZD6234 Following Single Ascending Dose Administration to Healthy Subjects Who Are Overweight or Obese
CompletedNCT05511025
AstraZenecaHealthy Participants
Start: 2022-09-20End: 2023-12-19Updated: 2023-12-26
A Phase I/II, Randomised, Single-blind, Placebo-controlled, Multiple-ascending-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD9550 Monotherapy and Co-administration of AZD9550 and AZD6234 in Participants Living with Obesity and Overweight with or without Type 2 Diabetes Mellitus
Active, not recruitingCTIS2023-504215-32-00
AstraZeneca ABOverweight and obesity
Start: 2023-09-28Target: 101Updated: 2025-10-15
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese
CompletedNCT06132841
AstraZenecaHealthy Participants
Start: 2023-11-13End: 2026-03-07Updated: 2026-04-03
Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234
CompletedNCT06845813
AstraZenecaRenal Impairment
Start: 2025-02-24End: 2025-09-30Updated: 2025-11-03
A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity
RecruitingNCT07013643
AstraZenecaHealthy Participants
Start: 2025-06-04End: 2026-12-25Target: 75Updated: 2026-03-03

Phase 2