AZD3480
Sponsors
AstraZeneca, Targacept Inc.
Conditions
ADHDAlzheimer DiseaseAlzheimer's DiseaseHealthyMetabolismSchizophrenia
Phase 1
Positron Emission Tomography Study Using 2-[18F]-F-A85380 to Determine α4β2 Neuronal Nicotinic Receptor Occupancy of AZD3480 After Oral Administration to Healthy Male Subjects
CompletedNCT00686413
Start: 2008-01-31End: 2008-08-31Updated: 2010-12-10
Investigate the Effect on the QT/QTc Interval of Repeated and Escalating Doses of AZD3480 During 6 Days
CompletedNCT00686179
Start: 2008-01-31End: 2008-08-31Updated: 2008-09-25
Drug Interaction Study Between AZD3480 and Warfarin
CompletedNCT00689637
Start: 2007-09-30End: 2009-02-28Target: 26Updated: 2009-07-02
Drug Interaction Study Between AZD3480 and Aripiprazole in Healthy Subjects
CompletedNCT00689559
Start: 2008-03-31End: 2009-04-30Target: 52Updated: 2009-07-02
Drug Interaction Study Between AZD3480 and Cytochrome P450
CompletedNCT00692510
Start: 2007-11-30End: 2008-09-30Target: 18Updated: 2008-11-26
Pharmacokinetic Interaction Between AZD3480 and Donepezil
TerminatedNCT00713765
Start: 2008-12-31End: 2008-12-31Updated: 2014-08-15
Study of Uptake, Break Down and Elimination of an Investigational Drug in Healthy Volunteers
TerminatedNCT00777361
Start: 2008-10-31End: 2009-10-31Updated: 2010-11-18
Phase 2
Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease
CompletedNCT00501111
Start: 2007-07-31End: 2008-08-31Updated: 2014-07-23
Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia
CompletedNCT00528905
Start: 2007-08-31End: 2008-11-30Target: 400Updated: 2008-11-25
An Exploratory Trial of AZD3480 (TC-1734) for the Treatment of Adult Attention-Deficit/Hyperactivity Disorder (ADHD)
CompletedNCT00683462
Start: 2008-05-31End: 2009-07-31Target: 24Updated: 2009-10-30
Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)
CompletedNCT01466088
Start: 2011-10-31End: 2014-05-31Updated: 2015-06-03