AZD1386
Sponsors
AstraZeneca
Conditions
Capsaicin Evoked PainChronic PainEsophageal SensitivityHealthy VolunteersHeat SensitivityNeuropathic PainPainPharmacokinetics
Phase 1
Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1386
CompletedNCT00690079
Start: 2008-02-29End: 2008-10-31Target: 69Updated: 2010-12-10
Study to Investigate the Effects Single Oral Dose of AZD1386 (Capsaicin)
CompletedNCT00692146
Start: 2008-01-31End: 2008-05-31Updated: 2008-06-06
Esophageal Hypersensitivity Study in Healthy Volunteers
CompletedNCT00711048
Start: 2008-06-30End: 2009-07-31Target: 45Updated: 2009-08-28
Formulation and Food Effect Study of AZD1386 in Healthy Volunteers
CompletedNCT00714337
Start: 2008-06-30End: 2008-08-31Target: 12Updated: 2010-12-10
AZD1386 Japanese Multiple Ascending Dosing Study
CompletedNCT00736658
Start: 2008-06-30End: 2008-09-30Target: 32Updated: 2009-09-30
Investigation of Rate+Extent of Excretion of Radioactivity in Urine+Faeces After Oral Administration of [14C]AZD1386
CompletedNCT00832169
Start: 2009-01-31End: 2009-02-28Target: 6Updated: 2009-04-28
Double-blind Placebo-controlled 2-part Study Assessing the Safety, Tolerability and PK of AZD1386 in Healthy Volunteers
TerminatedNCT00945178
Start: 2009-08-31End: 2009-09-30Updated: 2010-12-10
Phase 2
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
CompletedNCT00672646
Start: 2008-04-30End: 2008-06-30Updated: 2012-06-08
Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee
TerminatedNCT00878501
Start: 2009-03-31End: 2009-07-31Updated: 2012-06-04
Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain
TerminatedNCT00976534
Start: 2009-09-30End: 2010-02-28Target: 90Updated: 2009-12-23
Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD)
CompletedNCT01019928
Start: 2009-11-30End: 2011-01-31Updated: 2012-11-09